Description

(R)-1-(Methylamino)-2-Propanol Hcl CAS NO 131101-46-7 is a high-purity chiral intermediate and building block of significant importance in advanced organic synthesis. Its value lies in its defined stereochemistry, which is critical for producing enantiomerically pure compounds with specific biological activity. This product is essential for research and development laboratories and production facilities in the pharmaceutical and fine chemical industries, particularly for the synthesis of active pharmaceutical ingredients (APIs) and specialty chemicals.

Application

• Pharmaceutical Intermediate: A key chiral building block in the synthesis of enantiomerically pure active pharmaceutical ingredients (APIs), especially for β-blockers and other cardiovascular or neurological drugs.
• Asymmetric Synthesis: Used as a chiral auxiliary or resolving agent in stereoselective chemical reactions to control the formation of specific stereoisomers.
• Ligand and Catalyst Preparation: Serves as a precursor for the synthesis of chiral ligands used in asymmetric catalysis, such as in hydrogenation or oxidation reactions.
• Fine Chemical Production: Employed in the manufacture of high-value specialty chemicals, agrochemicals, and performance materials where optical purity is a requirement.
• Biochemical Research: Utilized in academic and industrial R&D for studying enzyme interactions, receptor binding, and other stereochemistry-dependent biological processes.

Basic Information

Product Name	(R)-1-(Methylamino)-2-Propanol Hcl
CAS No.	131101-46-7
Molecular Formula	C4H12ClNO
Molecular Weight	125.60 g/mol
Synonyms	(R)-1-(Methylamino)-2-propanol hydrochloride; (R)-1-Methylamino-2-propanol HCl; (R)-N-Methyl-2-amino-1-propanol hydrochloride; (R)-2-Hydroxypropylmethylamine hydrochloride; (R)-1-Amino-2-propanol, N-methyl-, hydrochloride; (R)-MAPA HCl; (R)-N-Methylalaninol hydrochloride; (R)-1-Methylamino-propan-2-ol hydrochloride
EINECS	Contact for details

Quality Control

Our (R)-1-(Methylamino)-2-Propanol Hcl is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity analysis by HPLC, to ensure it meets the high standards required for pharmaceutical and fine chemical applications. A Certificate of Analysis (COA) detailing identity, purity (assay), enantiomeric excess (e.e.), and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); the container must be kept tightly sealed to prevent absorption of atmospheric moisture, which can compromise quality.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.