Description

1-Bromo-2,4,5-Triisopropylbenzene is a high-purity, multi-substituted aromatic bromo compound, serving as a versatile and valuable intermediate in advanced organic synthesis. Its unique sterically hindered structure makes it an essential building block for creating complex molecules with tailored properties. This product is primarily targeted at R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty materials industries seeking to develop new active ingredients and functional compounds.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for creating sterically demanding molecular architectures.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and pesticides where the triisopropylbenzene backbone provides stability and specific bioactivity.
• Ligand and Catalyst Development: Serves as a bulky, electron-donating aryl group in the design of phosphine and N-heterocyclic carbene (NHC) ligands for transition metal catalysis.
• Material Science Research: Employed in the creation of organic semiconductors, liquid crystals, and polymers where precise steric and electronic properties are critical.
• Cross-Coupling Reactions: Acts as a substrate in Suzuki, Heck, and Buchwald-Hartwig amination reactions to form biaryl and other complex structures.
• Chemical Reference Standard: Supplied as a high-purity standard for analytical method development and quality control in chemical manufacturing.

Basic Information

Product Name	1-Bromo-2,4,5-Triisopropylbenzene
CAS No.	131003-16-2
Molecular Formula	C15H23Br
Molecular Weight	283.25 g/mol
Synonyms	2,4,5-Triisopropylbromobenzene; 2-Bromo-1,3,4-triisopropylbenzene; Benzene, 1-bromo-2,4,5-triisopropyl-; 1,3,4-Triisopropyl-2-bromobenzene; 2,4,5-Triisopropyl-1-bromobenzene
EINECS	Contact for details

Quality Control

Our 1-Bromo-2,4,5-Triisopropylbenzene is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, and NMR, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment. We support cGMP compliance for pharmaceutical applications and can tailor purity grades to meet specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from strong acids and incompatible materials. For long-term storage, consider under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or solid
Identification (IR)	Conforms to structure
Purity (HPLC/GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.