Description

(1R,4S)-4-Amino-Cyclopent-2-Enecarboxylic Acid Hydrochloride is a high-purity chiral building block of significant interest in advanced pharmaceutical synthesis. This compound serves as a critical intermediate for developing novel therapeutic agents, particularly in the fields of neurology and antiviral research. It is essential for research institutions and pharmaceutical companies engaged in the development of complex small molecule drugs and peptidomimetics.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of novel drug candidates targeting central nervous system (CNS) disorders.
• Antiviral Drug Development: Used in the research and production of potential antiviral compounds, including protease inhibitors.
• Peptidomimetics Synthesis: Acts as a constrained scaffold to mimic peptide secondary structures, enhancing metabolic stability and bioavailability.
• Asymmetric Synthesis: Employed in catalytic asymmetric reactions to introduce chirality into complex molecular architectures.
• Medicinal Chemistry Research: Utilized in structure-activity relationship (SAR) studies and lead optimization processes.
• Chemical Biology Probes: Incorporated into molecular probes for studying enzyme function and biological pathways.

Basic Information

Product Name	(1R,4S)-4-Amino-Cyclopent-2-Enecarboxylic Acid Hydrochloride
CAS No.	130931-85-0
Molecular Formula	C6H10ClNO2
Molecular Weight	163.60 g/mol
Synonyms	(1R,4S)-4-Amino-2-cyclopentene-1-carboxylic acid hydrochloride; (1R,4S)-4-Amino-1,2,3,4-tetrahydro-1,4-methano-1H-indene-2-carboxylic acid hydrochloride (related fused system); 4-Amino-2-cyclopentene-1-carboxylic acid hydrochloride, (1R,4S)-; cis-4-Amino-2-cyclopentene-1-carboxylic acid hydrochloride; ACCA hydrochloride; 4-ACPC hydrochloride; (1R,4S)-rel-4-Amino-2-cyclopentene-1-carboxylic acid hydrochloride
EINECS	Contact for details

Quality Control

Our (1R,4S)-4-Amino-Cyclopent-2-Enecarboxylic Acid Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets the stringent requirements for pharmaceutical R&D and cGMP intermediate applications. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming identity, purity, and chiral integrity.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere or in a desiccated environment after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Chiral Purity (HPLC)	≥99.0% ee
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.