Description

2-Pyrrolidinone,3-Amino-1-Hydroxy-4-Methyl-,(3R,4R)-(9Ci) is a high-purity, stereochemically defined chiral intermediate of significant importance in advanced organic synthesis. This compound matters for its role as a critical building block in the development of complex, biologically active molecules, particularly within the pharmaceutical sector. It is primarily needed by research institutions and manufacturers engaged in the synthesis of novel APIs, agrochemicals, and fine chemicals where precise stereochemistry is essential for efficacy and regulatory approval.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of novel Active Pharmaceutical Ingredients (APIs), especially in neurological and anti-infective drug discovery.
• Agrochemical Synthesis: Used in the research and development of advanced pesticides and herbicides with specific stereochemical requirements for enhanced activity.
• Fine Chemical Production: Serves as a versatile building block for creating complex, high-value specialty chemicals and ligands for catalysis.
• Biochemical Research: Employed in the study of enzyme inhibitors and the development of molecular probes due to its functionalized pyrrolidinone core.
• Asymmetric Catalysis: Can be utilized to develop or as a precursor for chiral auxiliaries and catalysts in stereoselective synthesis.

Basic Information

Product Name	2-Pyrrolidinone,3-Amino-1-Hydroxy-4-Methyl-,(3R,4R)-(9Ci)
CAS No.	130931-65-6
Molecular Formula	C5H10N2O2
Molecular Weight	130.15 g/mol
Synonyms	(3R,4R)-3-Amino-1-hydroxy-4-methylpyrrolidin-2-one; (3R,4R)-3-Amino-4-methyl-2-pyrrolidinone 1-ol; 3-Amino-1-hydroxy-4-methyl-2-pyrrolidinone, (3R,4R)-; 130931-65-6; (3R,4R)-AHMP; 4-Methyl-3-amino-1-hydroxy-2-pyrrolidinone (stereospecific); 1-Hydroxy-3-amino-4-methyl-2-pyrrolidinone, (3R,4R)-isomer
EINECS	Contact for details

Quality Control

Our 2-Pyrrolidinone,3-Amino-1-Hydroxy-4-Methyl-,(3R,4R)-(9Ci) is produced under strict quality management systems to ensure batch-to-batch consistency and high chemical purity. Each lot undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to meet the exacting standards required for pharmaceutical R&D. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to prevent moisture absorption, which may affect stability and performance.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.