Description

Cyclopropanecarboxylic Acid, 1-Amino-2,2-Dimethyl-, (1S)- (9Ci) is a high-purity, chiral cyclopropane derivative that serves as a critical building block in advanced organic synthesis. Its unique sterically hindered structure and defined stereochemistry make it invaluable for constructing complex molecular architectures with high precision. This compound is primarily sought after by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs) and agrochemicals, where it acts as a key chiral intermediate. CAS No. 130930-42-6.

Application

This specialized chiral intermediate is utilized in sophisticated synthetic pathways across several high-value industries:

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of novel therapeutic agents, including protease inhibitors and other small molecule drugs.
• Agrochemical Synthesis: Used in the production of advanced pesticides and herbicides, where its cyclopropane ring contributes to biological activity and stability.
• Asymmetric Catalysis Research: Serves as a valuable ligand precursor or substrate in the development and study of new asymmetric catalytic reactions.
• Material Science: Potential building block for specialty polymers and advanced materials requiring rigid, chiral components.
• Chemical Biology & Proteomics: Can be incorporated into molecular probes and activity-based protein profiling (ABPP) reagents due to its reactive amino and carboxylic acid functional groups.

Basic Information

Item	Detail
Product Name	Cyclopropanecarboxylic Acid, 1-Amino-2,2-Dimethyl-, (1S)- (9Ci)
CAS No.	130930-42-6
Molecular Formula	C7H13NO2
Molecular Weight	143.18 g/mol
Synonyms	(1S)-1-Amino-2,2-dimethylcyclopropanecarboxylic acid; (S)-1-Amino-2,2-dimethylcyclopropanecarboxylic acid; 1-Amino-2,2-dimethylcyclopropanecarboxylic acid, (S)-; L-1-Amino-2,2-dimethylcyclopropanecarboxylic acid; (S)-1-ADCP; Cyclopropanecarboxylic acid, 1-amino-2,2-dimethyl-, (1S)-; (S)-2,2-Dimethylcyclopropanecarboxylic acid-1-amine
EINECS	Contact for details

Quality Control

Our production of Cyclopropanecarboxylic Acid, 1-Amino-2,2-Dimethyl-, (1S)- adheres to stringent quality protocols to ensure batch-to-batch consistency and high chiral purity. Each lot undergoes comprehensive analytical testing, including chiral HPLC for enantiomeric excess determination. A Certificate of Analysis (COA) detailing purity, identity, and specific impurity profiles is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. This product is hygroscopic (moisture-sensitive) and should be handled under a dry inert atmosphere (e.g., nitrogen or argon) to prevent degradation. Recommended long-term storage at 2-8°C.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (ee, HPLC)	≥ 99.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.