Description

4,6-o-Benzylidene-3-o-tert-Butyldimethylsilyl-1-Tributylstannylglucal is a sophisticated, multi-protected carbohydrate derivative that serves as a pivotal advanced intermediate in synthetic organic chemistry. Its value lies in the strategic combination of protecting groups, which enables highly selective and efficient glycosylation reactions for the construction of complex oligosaccharides and glycoconjugates. This compound is essential for researchers and process chemists in the pharmaceutical and biotechnology sectors who are developing novel therapeutics, vaccines, and diagnostic agents that target carbohydrate-mediated biological processes. The CAS number for this material is 130912-41-3.

Application

• Glycosylation Reagent: A key building block for the stereoselective synthesis of O-glycosidic linkages in oligosaccharides and glycoconjugates.
• Pharmaceutical Intermediate: Critical for the research and development of carbohydrate-based drugs, including antibiotics, antiviral agents, and anticancer therapies.
• Glycobiology Research: Used to prepare defined glycan structures for studying protein-carbohydrate interactions, cell signaling, and immune response modulation.
• Vaccine Development: Employed in the synthesis of carbohydrate antigens for conjugate vaccine candidates against bacterial pathogens.
• Process Chemistry: Serves as an advanced intermediate in scalable synthetic routes for active pharmaceutical ingredients (APIs) with carbohydrate motifs.
• Chemical Biology Probe Synthesis: Facilitates the creation of labeled or modified sugars for imaging and mechanistic studies within biological systems.

Basic Information

Product Name	4,6-o-Benzylidene-3-o-tert-Butyldimethylsilyl-1-Tributylstannylglucal
CAS No.	130912-41-3
Molecular Formula	C33H58O5SiSn
Molecular Weight	669.59 g/mol
Synonyms	1-Tributylstannyl-4,6-O-benzylidene-3-O-(tert-butyldimethylsilyl)-D-glucal; Tributyl(4,6-O-benzylidene-3-O-tert-butyldimethylsilyl-1,2-dideoxy-D-lyxo-hex-1-enopyranos-2-yl)stannane; 1,2-Dideoxy-4,6-O-benzylidene-3-O-(tert-butyldimethylsilyl)-1-(tributylstannyl)-D-lyxo-hex-1-enopyranose; Benzylidene-TBDMS-Tributylstannylglucal; Protected Tributylstannyl Glucal Derivative
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. Each batch of 4,6-o-Benzylidene-3-o-tert-Butyldimethylsilyl-1-Tributylstannylglucal is characterized using advanced analytical techniques including NMR (¹H and ¹³C), HPLC, and mass spectrometry to confirm identity, purity, and stability. Certificates of Analysis (COA) detailing all specifications and test results are available upon request, supporting your regulatory and R&D documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (argon or nitrogen) in a cool, dry place. Recommended storage temperature is 2-8°C for long-term stability. The compound is moisture-sensitive and should be handled under anhydrous conditions.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.