Description

L-Alanine, n-[(2-Aminocyclopentyl)carbonyl]-n-methyl-, (1R-cis)- (9Ci) is a specialized, non-proteinogenic amino acid derivative featuring a unique cyclopentyl backbone. This compound is of significant interest in advanced pharmaceutical research and development, particularly as a sophisticated chiral building block or intermediate for complex organic synthesis. Its precise stereochemistry and functional groups make it a valuable scaffold for medicinal chemists targeting novel therapeutics, including protease inhibitors and other bioactive molecules.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of new active pharmaceutical ingredients (APIs), especially for targeted therapies.
• Medicinal Chemistry Research: Used as a constrained scaffold for designing and synthesizing novel drug candidates, such as enzyme inhibitors or receptor modulators.
• Peptidomimetics: Serves as a building block for creating peptide analogs with enhanced metabolic stability and bioavailability.
• Chemical Biology Probes: Utilized in the synthesis of specialized probes for studying enzyme mechanisms or protein-protein interactions.
• Asymmetric Synthesis: Acts as a chiral auxiliary or starting material in stereoselective synthesis routes for complex organic molecules.
• Reference Standard: Employed as a high-purity analytical standard in quality control and method development within R&D and manufacturing.

Basic Information

Item	Detail
Product Name	L-Alanine, n-[(2-Aminocyclopentyl)carbonyl]-n-methyl-, (1R-cis)- (9Ci)
CAS No.	130901-87-0
Molecular Formula	C10H18N2O2
Molecular Weight	198.26 g/mol
Synonyms	(1R,2S)-N-Methyl-2-(aminocyclopentane-1-carboxamido)propionamide; (1R-cis)-N-[(2-Aminocyclopentyl)carbonyl]-N-methyl-L-alanine; L-Alanine, N-[(2-aminocyclopentyl)carbonyl]-N-methyl-, (1R-cis)-; N-Methyl-N-[(1R,2S)-2-aminocyclopentylcarbonyl]-L-alanine; A constrained alanine derivative; Cyclopentane-based amino acid analog
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. We provide comprehensive analytical data to support research and development applications. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request for every batch, ensuring full traceability and reliability for your critical synthesis work.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Optical Rotation	Specific range provided per batch
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.