Description

1,4-Dichloro-2-(1,1,2,3,3,3-hexafluoropropoxy)-5-nitrobenzene is a high-value, multi-functional fluorinated aromatic intermediate designed for advanced chemical synthesis. Its unique structure, featuring both chloro and nitro substituents on a benzene ring linked to a hexafluoropropoxy group, makes it a critical building block for creating complex molecules with tailored properties. This compound is primarily sought after by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty materials sectors for applications requiring precise fluorination and derivatization.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of novel active pharmaceutical ingredients (APIs), particularly those targeting central nervous system (CNS) disorders or requiring enhanced metabolic stability and bioavailability via fluorine incorporation.
• Agrochemical Synthesis: Used in the research and development of next-generation herbicides, fungicides, and insecticides, where the fluorinated moiety can improve lipophilicity, membrane penetration, and environmental persistence.
• Liquid Crystal & OLED Materials: Acts as a building block for fluorinated components in electronic display materials, where its structure can influence dielectric anisotropy, viscosity, and thermal stability.
• Polymer Modification: Employed to introduce fluorinated side chains into polymers, enhancing properties such as chemical resistance, thermal stability, and surface characteristics for high-performance coatings and engineering plastics.
• Organic Synthesis & Catalysis Research: Provides a versatile scaffold for developing new ligands, catalysts, or reagents in asymmetric synthesis and cross-coupling reactions.

Basic Information

Item	Details
Product Name	1,4-Dichloro-2-(1,1,2,3,3,3-Hexafluoropropoxy)-5-Nitrobenzene
CAS No.	130841-23-5
Molecular Formula	C9H3Cl2F6NO3
Molecular Weight	358.02 g/mol
Synonyms	2,5-Dichloro-4-nitro-1-(1,1,2,3,3,3-hexafluoropropoxy)benzene; 1,4-Dichloro-2-(hexafluoropropoxy)-5-nitrobenzene; 5-Nitro-1,4-dichloro-2-(1,1,2,3,3,3-hexafluoropropoxy)benzene; 2-(1,1,2,3,3,3-Hexafluoropropoxy)-1,4-dichloro-5-nitrobenzene; 1,4-Dichloro-5-nitro-2-(1,1,2,3,3,3-hexafluoropropoxy)benzene; 130841-23-5; Benzene, 1,4-dichloro-2-(1,1,2,3,3,3-hexafluoropropoxy)-5-nitro-
EINECS	Contact for details

Quality Control

Our production of 1,4-Dichloro-2-(1,1,2,3,3,3-hexafluoropropoxy)-5-nitrobenzene adheres to stringent quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide detailed Certificates of Analysis (COA) with every shipment, documenting all critical specifications. Our quality system is designed to support cGMP and ISO 9001 standards, ensuring reliability for your most demanding R&D and scale-up projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be amber-colored or stored in light-resistant secondary packaging.

Specification

Item	Specification
Appearance	Off-white to pale yellow crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Purity (GC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.