Description

3,6-Dichloro-4-Iodopyridazine is a halogenated heterocyclic building block of significant interest in advanced organic synthesis. This compound matters for its role as a versatile intermediate in the development of active pharmaceutical ingredients (APIs) and agrochemicals, where its distinct substitution pattern enables precise molecular modifications. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing complex pyridazine-based molecules.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and infectious diseases.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides with specific modes of action.
• Material Science: Serves as a building block for creating functionalized polymers and liquid crystals with tailored electronic properties.
• Chemical Biology: Employed as a molecular probe or a tag in bioconjugation chemistry due to its reactive halogen sites.
• Cross-Coupling Reactions: The iodine substituent makes it an excellent substrate for palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Sonogashira) to create diverse biaryl structures.
• Nucleophilic Aromatic Substitution: The chlorines are susceptible to displacement by various nucleophiles, allowing for the introduction of amines, alkoxides, and thiols.

Basic Information

Product Name	3,6-Dichloro-4-Iodopyridazine
CAS No.	130825-13-7
Molecular Formula	C4HCl2IN2
Molecular Weight	274.87 g/mol
Synonyms	4-Iodo-3,6-dichloropyridazine; 3,6-Dichloro-4-iodopyridazine; 4-Iodo-3,6-dichloro-1,2-diazine; Pyridazine, 3,6-dichloro-4-iodo-; 130825-13-7; 3,6-Dichloro-4-iodo-1,2-diazine
EINECS	Contact for details

Quality Control

Our 3,6-Dichloro-4-Iodopyridazine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for research and process chemistry. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Heavy Metals	< 20 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.