Description

5-Oxo-L-Pro-1-[(Butyloxy)Carbonyl]-L-His-L-Pro-Nh2 is a synthetic peptide derivative of significant interest in advanced pharmaceutical research and development. This compound serves as a critical building block and intermediate for the synthesis of more complex bioactive peptides and peptidomimetics. It is primarily utilized by research institutions and pharmaceutical companies engaged in drug discovery, particularly for developing novel therapeutic agents targeting metabolic and neurological pathways.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel peptide-based drug candidates and active pharmaceutical ingredients (APIs).
• Biochemical Research: Used as a substrate or inhibitor in enzymatic studies and proteomics research to investigate biological pathways.
• Peptide Library Synthesis: Employed in combinatorial chemistry for the generation of diverse peptide libraries for high-throughput screening.
• Drug Discovery: Serves as a core scaffold for the development of peptidomimetics with enhanced stability and bioavailability.
• Reference Standard: Used as an analytical standard in quality control laboratories for method development and validation.

Basic Information

Product Name	5-Oxo-L-Pro-1-[(Butyloxy)Carbonyl]-L-His-L-Pro-Nh2
CAS No.	130817-94-6
Molecular Formula	C22H32N6O7
Molecular Weight	492.53 g/mol
Synonyms	Boc-His-Pro-NH2 (5-oxoproline derivative); L-Histidyl-L-prolinamide, N2-[(1,1-dimethylethoxy)carbonyl]-5-oxo-L-prolyl-; 5-Oxo-L-prolyl-N-[(1,1-dimethylethoxy)carbonyl]-L-histidyl-L-prolinamide; (S)-2-((S)-1-((tert-Butoxycarbonyl)-1H-imidazol-4-yl)methyl)-5-oxopyrrolidine-2-carboxamido)pyrrolidine-1-carboxamide; Boc-5-oxoprolyl-His-Pro-NH2; Peptide Synthesis Intermediate 130817-94-6
EINECS	Contact for details

Quality Control

Our 5-Oxo-L-Pro-1-[(Butyloxy)Carbonyl]-L-His-L-Pro-Nh2 is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via mass spectrometry and NMR, to ensure it meets the high standards required for research and pharmaceutical applications. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and analytical results is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms
Purity (HPLC)	≥ 97.0%
Assay	≥ 98.0% (on anhydrous basis)
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.