Description

n-Cbz-Nortropinone is a protected nortropinone derivative, serving as a crucial chiral building block and advanced pharmaceutical intermediate. Its primary value lies in enabling the stereoselective synthesis of complex bioactive molecules, particularly in the development of central nervous system (CNS) agents. This high-purity intermediate is essential for research and production within the pharmaceutical and fine chemical sectors, where precise molecular architecture is required.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of tropane alkaloid derivatives and related pharmacologically active compounds.
• Chiral Synthesis: Serves as a versatile chiral scaffold for constructing molecules with defined stereochemistry, critical for drug discovery.
• Neurological Research: Used in the research and development of potential therapeutics targeting neurotransmitter systems.
• Medicinal Chemistry: Employed in structure-activity relationship (SAR) studies and the optimization of lead compounds.
• Fine Chemical Production: Integral to multi-step synthetic routes for producing high-value specialty chemicals.
• Academic & Contract Research: Utilized in university laboratories and CROs (Contract Research Organizations) for methodological development and novel compound synthesis.

Basic Information

Item	Details
Product Name	n-Cbz-Nortropinone
CAS No.	130753-13-8
Molecular Formula	C16H19NO3
Molecular Weight	273.33 g/mol
Synonyms	N-Carbobenzyloxynortropinone; 8-Azabicyclo[3.2.1]octan-3-one, 8-[(phenylmethoxy)carbonyl]-; 8-[(Benzyloxy)carbonyl]-8-azabicyclo[3.2.1]octan-3-one; Cbz-Nortropinone; N-Cbz-8-azabicyclo[3.2.1]octan-3-one; Benzyl 3-oxo-8-azabicyclo[3.2.1]octane-8-carboxylate; Nortropinone N-Cbz derivative; 130753-13-8
EINECS	Contact for details

Quality Control

Our n-Cbz-Nortropinone is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC for assay and purity, and is supplied with a corresponding Certificate of Analysis (COA). We adhere to cGMP principles where applicable to support our clients' regulatory requirements in pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep the container tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Purity (HPLC)	≥ 98.5%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.