Description

Fmoc-D-Arg-Oh CAS NO 130752-32-8 is a high-purity, protected amino acid derivative essential for solid-phase peptide synthesis (SPPS). This compound serves as a critical building block for the controlled introduction of D-arginine residues, enabling the creation of complex peptides with enhanced stability and biological activity. It is primarily utilized by pharmaceutical R&D teams, biotechnology companies, and CROs engaged in the development of therapeutic peptides, peptide-based diagnostics, and biochemical research.

Application

• Solid-Phase Peptide Synthesis (SPPS): As a key Fmoc-protected amino acid for the automated synthesis of custom peptides.
• Therapeutic Peptide Development: For constructing peptide drug candidates, including antimicrobial peptides (AMPs) and hormone analogs.
• Bioconjugation and Probe Synthesis: Used in the preparation of labeled peptides for imaging, diagnostic assays, and target identification.
• Biochemical Research: As a reagent for studying enzyme-substrate interactions, receptor binding, and signal transduction pathways.
• Peptide Library Production: For generating diverse combinatorial libraries used in high-throughput screening for drug discovery.
• Material Science: Incorporation into peptide-based biomaterials and hydrogels for biomedical applications.

Basic Information

Product Name	Fmoc-D-Arg-Oh
CAS No.	130752-32-8
Molecular Formula	C₂₁H₂₄N₄O₄
Molecular Weight	396.44 g/mol
Synonyms	Fmoc-D-arginine; N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-D-arginine; D-Fmoc-arginine; Fmoc-D-Arg-OH; (R)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-5-guanidinopentanoic acid; N-α-Fmoc-D-arginine; Fmoc-D-Arg; FMOC-D-ARG-OH
EINECS	Contact for details

Quality Control

Our Fmoc-D-Arg-Oh is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity, typically ≥98% (by HPLC). Each lot undergoes comprehensive analytical testing including identification (IR, NMR), assay (HPLC), and control of specific impurities. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C. This product is hygroscopic (moisture-sensitive) and should be handled under dry conditions to prevent degradation. For long-term storage, consider desiccation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference
Assay (HPLC)	≥ 98.0%
Optical Rotation	Contact for details
Water Content (KF)	≤ 1.0%
Heavy Metals	≤ 20 ppm
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.