Description

(S)-Diethyl 2-(tert-Butoxycarbonylamino)Pentanedioate(Wx665212) is a high-purity, chiral N-Boc protected amino acid derivative, specifically the diethyl ester of (S)-2-(Boc-amino)glutaric acid. This compound serves as a critical protected building block in the synthesis of complex molecules, offering precise stereochemical control. It is primarily needed by pharmaceutical research and fine chemical synthesis teams for developing active pharmaceutical ingredients (APIs), peptides, and other biologically active compounds.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the multi-step synthesis of novel drug candidates and active pharmaceutical ingredients (APIs).
• Peptide Synthesis: Used as a protected glutamic acid derivative for the solid-phase or solution-phase construction of peptides and peptidomimetics.
• Asymmetric Synthesis: Serves as a starting material or intermediate in catalytic asymmetric transformations to create complex, enantiomerically pure molecules.
• Protecting Group Chemistry: The tert-butoxycarbonyl (Boc) group provides orthogonal protection for the amine functionality during complex synthetic sequences.
• Bioconjugation & Linker Chemistry: The carboxylic ester and protected amine functionalities can be modified to create linkers for bioconjugation or prodrug development.
• Academic & Industrial R&D: Employed in research laboratories for methodological development and the synthesis of custom organic compounds.

Basic Information

Item	Detail
Product Name	(S)-Diethyl 2-(tert-Butoxycarbonylamino)Pentanedioate(Wx665212)
CAS No.	130696-54-7
Molecular Formula	C14H25NO6
Molecular Weight	303.35 g/mol
Synonyms	(S)-Diethyl 2-((tert-Butoxycarbonyl)amino)pentanedioate; (S)-2-((tert-Butoxycarbonyl)amino)glutaric Acid Diethyl Ester; (S)-Diethyl N-Boc-glutamate; (S)-N-Boc-Glu(OEt)-OEt; (S)-Boc-Glu(OEt)-OEt; (S)-2-(Boc-amino)glutaric Acid Diethyl Ester; (S)-Diethyl 2-(Boc-amino)glutarate; Wx665212
EINECS	Contact for details

Quality Control

Our (S)-Diethyl 2-(tert-Butoxycarbonylamino)Pentanedioate is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for pharmaceutical research. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong acids and organic solvents. The container must be kept tightly closed to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.