Description

(S)-2-(1-Naphthylmethyl)Succinic Acid-1-Methyl Ester is a high-purity chiral intermediate of significant importance in advanced organic synthesis. This compound is valued for its role as a key building block in the production of enantiomerically pure pharmaceuticals and fine chemicals. It is primarily needed by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for developing active ingredients and novel materials.

Application

• Pharmaceutical Intermediate: A critical chiral synthon for the synthesis of enantiomerically pure active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and cardiovascular drug research.
• Agrochemical Synthesis: Used in the development of chiral pesticides and herbicides, where stereochemistry is crucial for biological activity and environmental safety.
• Asymmetric Catalysis: Serves as a precursor or ligand in the development of chiral catalysts for stereoselective chemical transformations.
• Fine Chemical Production: Employed in the manufacture of specialty chemicals, flavors, and fragrances requiring specific stereochemical configurations.
• Academic & Industrial Research: A valuable tool for chemists in methodological studies and the development of new synthetic routes for complex molecules.
• Material Science: Potential monomer or additive in the synthesis of specialized polymers with tailored optical or mechanical properties.

Basic Information

Product Name	(S)-2-(1-Naphthylmethyl)Succinic Acid-1-Methyl Ester
CAS No.	130693-96-8
Molecular Formula	C₁₇H₁₈O₄
Molecular Weight	286.32 g/mol
Synonyms	(S)-2-[(1-Naphthyl)methyl]butanedioic acid 1-methyl ester; (S)-1-Methoxy-1-oxo-3-[(naphthalen-1-yl)methyl]propane-2-carboxylic acid; (S)-Methyl 2-((1-naphthyl)methyl)succinate; (S)-2-(1-Naphthylmethyl)succinic acid methyl ester; Succinic acid, 2-[(1-naphthyl)methyl]-, 1-methyl ester, (S)-; Methyl (S)-2-(naphthalen-1-ylmethyl)succinate
EINECS	Contact for details

Quality Control

Our (S)-2-(1-Naphthylmethyl)Succinic Acid-1-Methyl Ester is produced under strict quality management systems to ensure batch-to-batch consistency and high enantiomeric purity. Each lot is characterized by advanced analytical techniques including HPLC, GC, and chiral analysis. Certificates of Analysis (COA) detailing identity, purity, enantiomeric excess, and impurity profiles are provided and available upon request to support your regulatory and R&D needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep the container tightly sealed to protect from moisture. This material is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Enantiomeric Purity (Chiral HPLC)	≥ 99.0% ee
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.