Description

(5R,7R)-8-Benzyloxy-7-Hydroxy-5-Methyl-5-Vinyl-Octanoic Acid Methyl Ester is a high-purity chiral intermediate of significant importance in advanced organic synthesis. This compound matters for its role as a key building block in the production of complex, biologically active molecules, offering precise stereochemical control. It is primarily needed by research institutions and pharmaceutical manufacturers engaged in the development of novel therapeutic agents, particularly in the synthesis of statin analogs and other fine chemicals.

Application

• Pharmaceutical Intermediate: A critical chiral synthon in the multi-step synthesis of HMG-CoA reductase inhibitors (statins) and other complex drug candidates.
• Organic Synthesis Research: Used in academic and industrial R&D for constructing complex molecular architectures with defined stereochemistry.
• Fine Chemical Production: Serves as a precursor in the manufacture of specialty chemicals requiring specific enantiomeric purity.
• Process Chemistry Development: Employed in scaling up synthetic routes from laboratory to pilot plant and commercial production.
• Reference Standard: Utilized as an analytical standard for quality control and method development in pharmaceutical analysis.

Basic Information

Product Name	(5R,7R)-8-Benzyloxy-7-Hydroxy-5-Methyl-5-Vinyl-Octanoic Acid Methyl Ester
CAS No.	130675-13-7
Molecular Formula	C19H26O5
Molecular Weight	334.41 g/mol
Synonyms	Methyl (5R,7R)-8-(Benzyloxy)-7-hydroxy-5-methyl-5-vinyloctanoate; (5R-trans)-8-(Phenylmethoxy)-7-hydroxy-5-methyl-5-vinyloctanoic Acid Methyl Ester; (5R,7R)-8-(Benzyloxy)-7-hydroxy-5-methyl-5-vinyl-octanoic Acid Methyl Ester; Statin Side Chain Intermediate; (5R,7R)-Lactone Open Chain Benzyl Ether; (5R,7R)-BMVOM; A Chiral Synthon for Atorvastatin
EINECS	Contact for details

Quality Control

Our (5R,7R)-8-Benzyloxy-7-Hydroxy-5-Methyl-5-Vinyl-Octanoic Acid Methyl Ester is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral HPLC and NMR, to ensure high enantiomeric and chemical purity suitable for pharmaceutical applications. Certificates of Analysis (COA) with detailed chromatographic data are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Keep the container tightly sealed in a dry environment to maintain product integrity.

Specification

Item	Specification
Appearance	Colorless to pale yellow viscous liquid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Enantiomeric Purity (Chiral HPLC)	≥ 98.5% (5R,7R)
Specific Rotation	Contact for details
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.