Description

(3As)-4-Bromo-3A 5A 6A 6B-Tetrahydro-2 CAS NO 130669-74-8 is a specialized brominated heterocyclic compound that serves as a critical chiral building block and intermediate in advanced organic synthesis. Its unique stereochemistry and reactive bromine moiety make it invaluable for constructing complex molecular architectures with high precision. This high-purity intermediate is primarily sought after by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs), agrochemicals, and sophisticated materials science applications.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of novel therapeutic agents, particularly in central nervous system (CNS) and antiviral drug candidates.
• Agrochemical Synthesis: Used in the production of advanced, stereospecific pesticides and herbicides where specific chirality impacts biological activity.
• Asymmetric Catalysis Ligand Precursor: Serves as a starting material for synthesizing sophisticated chiral ligands used in asymmetric hydrogenation and cross-coupling reactions.
• Material Science Research: Employed in the development of chiral organic frameworks and advanced polymeric materials with specific optical properties.
• Academic & Process Chemistry: A valuable reagent for methodological studies in organic chemistry, enabling novel synthetic routes and ring-forming reactions.
• Fine Chemical Production: Integral to the multi-step synthesis of complex, high-value specialty chemicals for various industrial sectors.

Basic Information

Product Name	(3As)-4-Bromo-3A 5A 6A 6B-Tetrahydro-2
CAS No.	130669-74-8
Molecular Formula	C6H8BrN
Molecular Weight	174.04 g/mol
Synonyms	4-Bromo-3a,5a,6a,6b-tetrahydro-2H-cyclopropa[3,4]pyrrolo[1,2-c]oxazole; (3aR,5aS,6aS,6bR)-4-Bromo-3a,5a,6a,6b-tetrahydro-2H-cyclopropa[3,4]pyrrolo[1,2-c]oxazole; 4-Bromo-3a,5a,6a,6b-tetrahydro-2H-cyclopropa[3,4]pyrrolo[1,2-c]oxazole; Brominated Tetrahydrocyclopropapyrrolooxazole; Chiral Bromo-oxazole Fused System; Advanced Brominated Heterocycle; API Intermediate 130669-74-8
EINECS	Contact for details

Quality Control

Every batch of (3As)-4-Bromo-3A 5A 6A 6B-Tetrahydro-2 is manufactured under strict quality management systems. We employ advanced analytical techniques including HPLC, GC, NMR, and chiral analysis to ensure high chemical and enantiomeric purity, meeting the stringent requirements of pharmaceutical R&D. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). The product is light-sensitive and should be handled under an inert atmosphere when appropriate to maintain stability. Keep away from strong acids and incompatible organic solvents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.