Description

4-Isoxazoleaceticacid,α-Amino-2,5-Dihydro-5-Oxo-,(R)-(9Ci) is a high-purity chiral building block and advanced pharmaceutical intermediate. This compound is valued for its unique isoxazole-acetic acid hybrid structure, which is integral to the synthesis of complex bioactive molecules. It is primarily sought after by research institutions and pharmaceutical manufacturers engaged in the development of novel therapeutics, particularly in areas requiring stereochemically defined intermediates.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of new active pharmaceutical ingredients (APIs), especially those targeting neurological and metabolic disorders.
• Agrochemical Synthesis: Used in the creation of advanced, high-efficacy pesticide and herbicide molecules with specific stereochemical requirements.
• Bioconjugation & Probe Development: Serves as a reactive handle for bioconjugation chemistry in the development of diagnostic probes and targeted drug delivery systems.
• Asymmetric Catalysis Research: Employed as a substrate or ligand precursor in academic and industrial research focused on developing new asymmetric synthetic methodologies.
• Peptidomimetic Chemistry: Incorporated into the design and synthesis of peptidomimetics and constrained peptides to modulate biological activity and stability.

Basic Information

Product Name	4-Isoxazoleaceticacid,α-Amino-2,5-Dihydro-5-Oxo-,(R)-(9Ci)
CAS No.	130645-62-4
Molecular Formula	C5H6N2O4
Molecular Weight	158.11 g/mol
Synonyms	(R)-2-Amino-2-(5-oxo-2,5-dihydroisoxazol-4-yl)acetic acid; (R)-α-Amino-2,5-dihydro-5-oxo-4-isoxazoleacetic acid; (R)-Amino-Dihydro-Oxo-Isoxazoleacetic Acid; 4-Isoxazoleacetic acid, α-amino-2,5-dihydro-5-oxo-, (R)-; (R)-2-Amino-2-(5-oxo-4,5-dihydro-1,2-oxazol-4-yl)acetic acid; (R)-AODIOA
EINECS	Contact for details

Quality Control

Our 4-Isoxazoleaceticacid,α-Amino-2,5-Dihydro-5-Oxo-,(R)-(9Ci) is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets the stringent requirements for pharmaceutical R&D. Certificates of Analysis (COA) detailing purity, enantiomeric excess, and impurity profiles are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.