Description

8-Amino-5,6,7,8-Tetrahydronaphthalene-2-Carboxylic Acid Hcl is a high-purity, functionalized tetralin derivative that serves as a critical chiral building block in advanced organic synthesis. Its value lies in the unique combination of a rigid, partially saturated naphthalene core with both amino and carboxylic acid functional groups, enabling the construction of complex, stereodefined molecular architectures. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for developing novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of complex drug candidates, particularly in central nervous system (CNS) and cardiovascular therapeutic areas.
• Agrochemical Research: Used in the development of novel herbicides, fungicides, and insecticides that require specific stereochemistry for optimal activity.
• Ligand and Catalyst Development: Serves as a precursor for creating chiral ligands and organocatalysts used in asymmetric synthesis.
• Fine Chemical Synthesis: Employed in the multi-step synthesis of specialty chemicals, dyes, and advanced materials.
• Academic & R&D: A valuable reagent for methodological studies in organic chemistry and medicinal chemistry research programs.

Basic Information

Product Name	8-Amino-5,6,7,8-Tetrahydronaphthalene-2-Carboxylic Acid Hcl
CAS No.	130532-64-8
Molecular Formula	C11H14ClNO2
Molecular Weight	227.69 g/mol
Synonyms	8-Amino-1,2,3,4-tetrahydronaphthalene-2-carboxylic acid hydrochloride; 2-Carboxy-5,6,7,8-tetrahydronaphthalen-1-amine hydrochloride; 5,6,7,8-Tetrahydro-8-amino-2-naphthoic acid hydrochloride; 8-Amino-5,6,7,8-tetrahydro-2-naphthoic acid HCl; 1-Amino-5,6,7,8-tetrahydronaphthalene-2-carboxylic acid hydrochloride; ATNCA-HCl; (8-Amino-5,6,7,8-tetrahydronaphthalen-2-yl)formic acid hydrochloride
EINECS	Contact for details

Quality Control

Our production of 8-Amino-5,6,7,8-Tetrahydronaphthalene-2-Carboxylic Acid Hcl adheres to stringent quality management protocols. Every batch undergoes comprehensive analytical testing, including chiral purity assessment, to ensure it meets the exacting standards required for pharmaceutical and advanced synthetic applications. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided and available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Chiral Purity (HPLC)	≥99.0% ee
Loss on Drying	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm
Related Substances (HPLC)	Individual impurity ≤0.5%; Total impurities ≤1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.