Description

1-Methyl-4-(Trifluoromethyl)-1H-Pyrrole-3-Carboxylic Acid CAS NO 130530-01-7 is a high-value, fluorinated pyrrole derivative that serves as a critical building block in advanced organic synthesis. Its unique structure, featuring a trifluoromethyl group, imparts desirable properties such as enhanced metabolic stability and lipophilicity to target molecules. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, where it is used to create novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel active pharmaceutical ingredients (APIs), particularly in medicinal chemistry programs targeting CNS disorders, inflammation, and oncology.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where the trifluoromethyl group can improve biological activity and environmental stability.
• Material Science Precursor: Employed in the synthesis of specialized polymers, ligands, and organic electronic materials that benefit from fluorine incorporation.
• Chemical Research & Development: Serves as a versatile scaffold in academic and industrial R&D for exploring new chemical spaces and reaction methodologies.
• Ligand and Catalyst Design: Useful for constructing complex chelating agents and organocatalysts used in asymmetric synthesis and metal complexation.

Basic Information

Product Name	1-Methyl-4-(Trifluoromethyl)-1H-Pyrrole-3-Carboxylic Acid
CAS No.	130530-01-7
Molecular Formula	C7H6F3NO2
Molecular Weight	193.12 g/mol
Synonyms	1-Methyl-4-(trifluoromethyl)-1H-pyrrole-3-carboxylic acid; 4-(Trifluoromethyl)-1-methyl-1H-pyrrole-3-carboxylic acid; 1-Methyl-4-trifluoromethylpyrrole-3-carboxylic acid; 3-Carboxy-1-methyl-4-(trifluoromethyl)pyrrole; 130530-01-7; 1H-Pyrrole-3-carboxylic acid, 1-methyl-4-(trifluoromethyl)-
EINECS	Contact for details

Quality Control

Our 1-Methyl-4-(Trifluoromethyl)-1H-Pyrrole-3-Carboxylic Acid is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide detailed Certificates of Analysis (COA) with each shipment, documenting all critical quality attributes. Our production adheres to cGMP principles where applicable, ensuring reliability for your most demanding synthesis workflows.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); keep the container tightly sealed in a dry environment to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.