Description

Zanamivir Amine CAS NO 130525-62-1 is a key pharmaceutical intermediate, specifically the amine precursor in the synthesis of the antiviral drug Zanamivir. This high-purity building block is critical for ensuring the efficacy and safety of the final active pharmaceutical ingredient (API). It is primarily required by pharmaceutical manufacturers and advanced research institutions engaged in the development and production of neuraminidase inhibitors for combating influenza viruses.

Application

• Primary Intermediate for the synthesis of Zanamivir, an antiviral medication used to treat and prevent influenza A and B.
• Research & Development of new antiviral agents and analogs targeting viral neuraminidase.
• Pharmaceutical Manufacturing as a controlled starting material in GMP-compliant API production processes.
• Reference Standard for analytical method development and quality control in pharmaceutical laboratories.
• Process Chemistry studies for optimizing synthetic routes and scaling up production.

Basic Information

Product Name	Zanamivir Amine
CAS No.	130525-62-1
Molecular Formula	C12H20N4O7
Molecular Weight	332.31 g/mol
Synonyms	5-Acetamido-4-guanidino-2,6-anhydro-3,4,5-trideoxy-D-glycero-D-galacto-non-2-enonic acid amine; (2R,3R,4S)-3-Acetamido-4-guanidino-2-((1R,2R)-1,2,3-trihydroxypropyl)-3,4-dihydro-2H-pyran-6-carboxylic acid amine; Zanamivir precursor; GG167 amine; 4-Guanidino-2,4-dideoxy-2,3-dehydro-N-acetylneuraminic acid amine; Relenza intermediate
EINECS	Contact for details

Quality Control

Our Zanamivir Amine is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral purity determination, and identification by IR and NMR spectroscopy, to ensure it meets the stringent requirements for pharmaceutical intermediates. Certificates of Analysis (COA) with full traceability are provided and can be tailored to meet specific customer or regulatory standards (e.g., ICH guidelines).

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Residual Solvents (GC)	Meets ICH Q3C guidelines
Water Content (KF)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.