Description

3'-Azido-3'-Deoxythymidine Monophosphate Diglyceride is a specialized nucleoside monophosphate prodrug derivative, designed for enhanced cellular delivery and metabolic stability. This compound is critical for advanced pharmaceutical research and development, particularly in the targeted delivery of antiviral and anticancer agents. It serves as a key intermediate and active pharmaceutical ingredient (API) for researchers and manufacturers in the life sciences sector, enabling the creation of next-generation therapeutics.

Application

• Antiviral Prodrug Development: Serves as a critical building block for synthesizing prodrugs targeting HIV and other viral infections.
• Oncology Research: Used in the development of nucleotide analogs for cancer therapy, leveraging its modified structure for improved tumor targeting.
• Pharmaceutical Intermediates: Acts as a high-value intermediate in the multi-step synthesis of complex active pharmaceutical ingredients (APIs).
• Bioconjugation & Drug Delivery Systems: The diglyceride moiety facilitates incorporation into liposomal formulations or nanoparticle carriers for enhanced bioavailability.
• Biochemical Research: Utilized as a substrate or inhibitor in enzymatic studies related to nucleotide metabolism.
• Preclinical Studies: Employed in pharmacokinetic and pharmacodynamic evaluations of novel nucleoside-based therapies.

Basic Information

Product Name	3'-Azido-3'-Deoxythymidine Monophosphate Diglyceride
CAS No.	130466-13-6
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	AZT Monophosphate Diglyceride; 3'-Azido-3'-deoxythymidine 5'-monophosphate diglyceride ester; AZT-MP-DG; Stavudine analog prodrug; Nucleoside monophosphate lipid conjugate; Thymidine azido monophosphate diglyceride
EINECS	Contact for details

Quality Control

Our 3'-Azido-3'-Deoxythymidine Monophosphate Diglyceride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets exacting standards for research and development. Certificates of Analysis (COA) with detailed chromatographic data are provided to guarantee traceability, consistency, and reliability for your critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (typically 15-25°C). The product is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC/IR)	Conforms to reference standard
Purity (HPLC)	≥ 95.0%
Related Substances (HPLC)	Individual impurity ≤ 2.0%
Water Content (KF)	≤ 5.0%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.