Description

cis-(+/-)-1-(Aminomethyl)-3,4-Dihydro-3-Phenyl-1H-2-Benzopyran-5,6-Diol Hydrochloride CAS NO 130465-39-3 is a high-purity, synthetic organic compound belonging to the benzopyran class, characterized by its chiral center and hydrochloride salt form. This compound is valued for its role as a critical pharmaceutical intermediate and a versatile building block in advanced organic synthesis. It is primarily sought by research institutions and manufacturers in the pharmaceutical and fine chemical industries for developing novel therapeutic agents.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of central nervous system (CNS) active drugs and other therapeutic molecules.
• Organic Synthesis Building Block: Utilized in the construction of complex heterocyclic compounds and natural product analogs due to its fused benzopyran structure.
• Medicinal Chemistry Research: Serves as a core scaffold for structure-activity relationship (SAR) studies and the discovery of new bioactive compounds.
• Precursor for Chiral Ligands: Can be further functionalized to create chiral ligands for asymmetric catalysis.
• Reference Standard: Used as an analytical standard in quality control laboratories for method development and validation.

Basic Information

Product Name	cis-(+/-)-1-(Aminomethyl)-3,4-Dihydro-3-Phenyl-1H-2-Benzopyran-5,6-Diol Hydrochloride
CAS No.	130465-39-3
Molecular Formula	C₁₇H₁₈ClNO₃
Molecular Weight	319.78 g/mol
Synonyms	1H-2-Benzopyran-5,6-diol, 1-(aminomethyl)-3,4-dihydro-3-phenyl-, hydrochloride, (3R-cis)-; (3R-cis)-1-(Aminomethyl)-3,4-dihydro-3-phenyl-1H-2-benzopyran-5,6-diol hydrochloride; cis-1-(Aminomethyl)-3,4-dihydro-3-phenyl-1H-2-benzopyran-5,6-diol HCl; 1-(Aminomethyl)-3,4-dihydro-3-phenyl-1H-2-benzopyran-5,6-diol hydrochloride (racemic cis-isomer); NSC 339579; A-77636 Hydrochloride (common research name).
EINECS	Contact for details

Quality Control

Our cis-(+/-)-1-(Aminomethyl)-3,4-Dihydro-3-Phenyl-1H-2-Benzopyran-5,6-Diol Hydrochloride is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.