Description

3-Quinolinecarboxylic Acid, 1-Cyclopropyl-6-Fluoro-1,4-Dihydro-4-Oxo- is a high-purity, advanced pharmaceutical intermediate belonging to the fluoroquinolone carboxylic acid class. This compound is critical for the synthesis of next-generation antibacterial agents, offering a key structural moiety for potent antimicrobial activity. It is primarily sought by pharmaceutical R&D and manufacturing sectors for the development of novel antibiotic therapies.

Application

• Key Intermediate for Fluoroquinolone Antibiotics: Serves as a crucial building block in the synthesis of advanced broad-spectrum antibacterial agents.
• Pharmaceutical Research & Development: Used in medicinal chemistry for the discovery and optimization of new antimicrobial drug candidates.
• Active Pharmaceutical Ingredient (API) Manufacturing: Employed in the commercial-scale production of finished dosage forms for antibiotic treatments.
• Chemical Synthesis Reference Standard: Acts as a high-purity standard for analytical method development and quality control in pharmaceutical labs.
• Process Chemistry & Scale-Up: Utilized in pilot plants and manufacturing facilities for process optimization and validation studies.

Basic Information

Product Name	3-Quinolinecarboxylic Acid, 1-Cyclopropyl-6-Fluoro-1,4-Dihydro-4-Oxo-
CAS No.	130436-10-1
Molecular Formula	C₁₃H₁₀FNO₃
Molecular Weight	247.22 g/mol
Synonyms	1-Cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-3-quinolinecarboxylic acid; 1-Cyclopropyl-6-fluoro-4-oxo-1,4-dihydroquinoline-3-carboxylic acid; 6-Fluoro-1-cyclopropyl-7-chloro-1,4-dihydro-4-oxo-3-quinolinecarboxylic acid (related derivative); Fleroxacin intermediate; Fluoroquinolone intermediate; Quinoline-3-carboxylic acid derivative; AM-833 intermediate; Ro 23-6240 intermediate
EINECS	Contact for details

Quality Control

Our 3-Quinolinecarboxylic Acid, 1-Cyclopropyl-6-Fluoro-1,4-Dihydro-4-Oxo- is manufactured under strict quality management systems. Every batch is subjected to rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specifications and test results. Our production adheres to cGMP guidelines suitable for pharmaceutical intermediate applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept tightly sealed and away from moisture and direct light exposure. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.5%
Related Substances (HPLC)	Total impurities ≤ 1.5% Any single impurity ≤ 0.5%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.