Description

(S)-(2-Amino-1-Phenyl-Ethyl)-Carbamic Acid Benzyl Ester is a high-purity chiral intermediate of significant importance in asymmetric synthesis. This compound is a critical building block for the development of active pharmaceutical ingredients (APIs) and fine chemicals, enabling the production of enantiomerically pure substances. It is primarily needed by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for the synthesis of complex molecules.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the synthesis of enantiomerically pure drugs, particularly in central nervous system (CNS) and cardiovascular therapeutic areas.
• Asymmetric Synthesis: Used as a precursor for chiral catalysts, ligands (e.g., for transition metal complexes), and auxiliaries in stereoselective reactions.
• Peptidomimetics Research: Serves as a protected amino acid derivative in the design and synthesis of peptide analogs and mimetics for drug discovery.
• Agrochemical Development: Employed in the research and production of chiral pesticides and herbicides where specific stereochemistry is required for biological activity.
• Academic & Industrial R&D: A valuable reagent for methodological development in organic chemistry and for scaling up novel synthetic routes.
• Fine Chemical Production: Integral to the manufacture of specialty chemicals, flavors, and fragrances that require high enantiomeric purity.

Basic Information

Product Name	(S)-(2-Amino-1-Phenyl-Ethyl)-Carbamic Acid Benzyl Ester
CAS No.	130406-36-9
Molecular Formula	C₁₆H₁₈N₂O₂
Molecular Weight	270.33 g/mol
Synonyms	(S)-Benzyl (2-amino-1-phenylethyl)carbamate; (S)-Cbz-1-Phenylethylenediamine; (S)-N-Cbz-1,2-Diphenylethylenediamine (common misnomer); (S)-N-[(Benzyloxy)carbonyl]-1-phenylethane-1,2-diamine; (S)-2-[(Benzyloxycarbonyl)amino]-1-phenylethylamine; (S)-Z-1-Phenylethylenediamine; (S)-α-Methylbenzyl Z-amine; (S)-1-Phenylethane-1,2-diamine, N-Cbz protected.
EINECS	Contact for details

Quality Control

Our (S)-(2-Amino-1-Phenyl-Ethyl)-Carbamic Acid Benzyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high chemical and chiral purity, meeting the stringent requirements for pharmaceutical R&D and production. Certificates of Analysis (COA) detailing purity, enantiomeric excess, and impurity profiles are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed in a dry environment to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.