Description

Cbz-(S)-2-Phenylglycinol is a high-purity, enantiomerically pure chiral building block and intermediate. This compound is of significant value in asymmetric synthesis and pharmaceutical research, serving as a key precursor for the development of active pharmaceutical ingredients (APIs) and fine chemicals. It is primarily needed by research institutions, pharmaceutical companies, and fine chemical manufacturers engaged in the synthesis of peptidomimetics, chiral ligands, and complex organic molecules.

Application

• Pharmaceutical Intermediate: A critical chiral synthon for the synthesis of various APIs, particularly in oncology and neurology drug discovery.
• Asymmetric Synthesis: Used as a chiral auxiliary or building block in stereoselective reactions to introduce the (S)-2-phenylglycinol moiety.
• Peptidomimetics & PROTACs: Integral for constructing peptide-like molecules and Proteolysis Targeting Chimeras (PROTACs) due to its amine and alcohol functionalities.
• Catalyst & Ligand Preparation: Serves as a precursor for chiral catalysts and ligands used in homogeneous catalysis.
• Academic & Industrial R&D: Employed in research laboratories for method development and exploring new synthetic pathways.
• Fine Chemical Production: Used in the multi-step synthesis of specialty chemicals and advanced materials.

Basic Information

Product Name	Cbz-(S)-2-Phenylglycinol
CAS No.	130406-31-4
Molecular Formula	C16H17NO3
Molecular Weight	271.31 g/mol
Synonyms	(S)-2-(((Benzyloxy)carbonyl)amino)-2-phenylethanol; (S)-N-Carbobenzoxy-2-phenylglycinol; (S)-Cbz-Phenylglycinol; (S)-N-Cbz-2-Phenylglycinol; (S)-2-(Benzyloxycarbonylamino)-2-phenylethanol; (S)-2-Amino-2-phenylethanol N-Cbz derivative; Benzyl (S)-(2-hydroxy-1-phenylethyl)carbamate; Z-(S)-Phenylglycinol
EINECS	Contact for details

Quality Control

Our Cbz-(S)-2-Phenylglycinol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification by HPLC, to ensure compliance with high-grade standards for research and pharmaceutical applications. A comprehensive Certificate of Analysis (COA) detailing purity, enantiomeric excess, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Heavy Metals	< 10 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.