Description

17-Benzoyloxy-11-Hydroxy-3,20-Dioxo-1,4-Pregnadien-21-Al Hemiacetal is a high-purity, complex steroid derivative with significant synthetic utility. This compound serves as a critical advanced intermediate in the pharmaceutical synthesis of potent corticosteroid APIs, enabling the development of next-generation anti-inflammatory and immunosuppressive therapies. It is essential for R&D laboratories and manufacturing facilities specializing in steroid chemistry, process development, and the production of high-value active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: A key building block in the multi-step synthesis of novel corticosteroid drugs and their analogs.
• Steroid Research & Development: Used in academic and industrial R&D for exploring new chemical entities (NCEs) with modified biological activity.
• Process Chemistry: Employed in route scouting and optimization for the commercial-scale production of steroid-based pharmaceuticals.
• Reference Standard: Serves as a high-purity analytical standard for quality control and method development in pharmaceutical analysis.
• Biochemical Studies: Utilized in studies investigating steroid receptor interactions and metabolic pathways.

Basic Information

Product Name	17-Benzoyloxy-11-Hydroxy-3,20-Dioxo-1,4-Pregnadien-21-Al Hemiacetal
CAS No.	130399-79-0
Molecular Formula	C29H32O6
Molecular Weight	476.56 g/mol
Synonyms	21-Hydroxy-11β,17α-dihydroxypregna-1,4-diene-3,20-dione 17-benzoate; 11β,17α,21-Trihydroxypregna-1,4-diene-3,20-dione 17-benzoate; 17α-Benzoyloxy-11β-hydroxy-21-aldehyde pregn-1,4-diene-3,20-dione hemiacetal; Betamethasone 17-benzoate intermediate; Pregna-1,4-diene-3,20-dione, 17-(benzoyloxy)-11,21-dihydroxy-, (11β)-; 11β-Hydroxy-17α-(benzoyloxy)pregna-1,4-diene-3,20-dione-21-al hemiacetal
EINECS	Contact for details

Quality Control

Our 17-Benzoyloxy-11-Hydroxy-3,20-Dioxo-1,4-Pregnadien-21-Al Hemiacetal is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, identity confirmation by IR and NMR, and residual solvent analysis, to ensure it meets the stringent requirements for pharmaceutical intermediates. Certificates of Analysis (COA) detailing all specifications are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%
Loss on Drying	≤ 1.0%
Residual Solvents (GC)	Complies with ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.