Description

4-{[tert-Butyl(Diphenyl)Silyl]Oxy}Butan-1-Ol is a high-purity organosilicon-protected alcohol derivative, serving as a critical building block in advanced organic synthesis. This compound is valued for its role in introducing protected hydroxyl functionality, enabling complex multi-step reactions with high selectivity and yield. It is primarily utilized by research institutions and industrial R&D departments in the pharmaceutical, agrochemical, and specialty chemical sectors for the development of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key synthon in the multi-step synthesis of complex drug candidates, particularly where selective protection and deprotection of alcohol groups is required.
• Agrochemical Synthesis: Used in the research and development of advanced pesticides and herbicides, contributing to the creation of molecules with specific biological activity.
• Peptide & Nucleotide Chemistry: Employed as a protecting group reagent in the synthesis of oligonucleotides and modified peptides, preventing unwanted side reactions.
• Material Science Research: Acts as a precursor or modifying agent in the development of novel silicon-containing polymers and advanced organic materials.
• Academic & Process Chemistry: Serves as a valuable tool for methodological development in organic synthesis and for scaling up synthetic routes in process chemistry.

Basic Information

Product Name	4-{[tert-Butyl(Diphenyl)Silyl]Oxy}Butan-1-Ol
CAS No.	130372-07-5
Molecular Formula	C20H28O2Si
Molecular Weight	328.52 g/mol
Synonyms	1-Butanol, 4-[[(1,1-dimethylethyl)diphenylsilyl]oxy]-; 4-(tert-Butyldiphenylsilyloxy)butan-1-ol; 4-(TBDPSO)butan-1-ol; 4-[[(1,1-Dimethylethyl)diphenylsilyl]oxy]-1-butanol; 4-Hydroxybutyl tert-butyldiphenylsilyl ether; TBDPS-protected 4-hydroxybutanol; 4-O-TBDPS-butanol
EINECS	Contact for details

Quality Control

Our 4-{[tert-Butyl(Diphenyl)Silyl]Oxy}Butan-1-Ol is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and Karl Fischer titration, to ensure identity, purity, and consistency. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment, supporting compliance with cGMP and ISO 9001 standards for research and development use.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption, which can compromise product stability and performance.

Specification

Item	Specification
Appearance	Colorless to pale yellow viscous liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.