Description

tert-Butyl (3-(Aminomethyl)Cyclobutyl)Carbamate is a versatile and high-purity chemical intermediate, specifically a Boc-protected cyclobutylamine derivative, essential for advanced organic synthesis. Its primary value lies in providing a protected primary amine functionality, enabling precise and efficient construction of complex molecular architectures in controlled environments. This compound is critically needed by research and development chemists and process scale-up teams within the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly in medicinal chemistry programs targeting central nervous system (CNS) disorders, inflammation, and metabolic diseases.
• Peptidomimetic Synthesis: Used to introduce constrained, non-natural amino acid motifs into peptide backbones to enhance metabolic stability and biological activity.
• Agrochemical Research: Serves as a precursor in the development of new herbicides, fungicides, and insecticides with improved efficacy and environmental profiles.
• Ligand and Catalyst Development: Employed in the creation of novel chiral ligands and organocatalysts for asymmetric synthesis applications.
• Chemical Biology Probes: Utilized to synthesize molecular probes for studying enzyme function and protein-protein interactions.
• Custom Synthesis and Contract Manufacturing: A critical starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) producing specialized compounds for clients.

Basic Information

Product Name	tert-Butyl (3-(Aminomethyl)Cyclobutyl)Carbamate
CAS No.	130369-10-7
Molecular Formula	C11H21N2O2
Molecular Weight	213.30 g/mol
Synonyms	1. tert-Butyl N-[3-(aminomethyl)cyclobutyl]carbamate 2. 3-(Aminomethyl)cyclobutanamine, N-Boc-protected 3. Boc-3-(Aminomethyl)cyclobutylamine 4. N-Boc-3-(Aminomethyl)cyclobutylamine 5. (3-(Aminomethyl)cyclobutyl)carbamic acid tert-butyl ester 6. 1,1-Dimethylethyl N-[3-(aminomethyl)cyclobutyl]carbamate 7. 130369-10-7 8. BOC-AMCB
EINECS	Contact for details

Quality Control

Our tert-Butyl (3-(Aminomethyl)Cyclobutyl)Carbamate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis by GC, to ensure it meets the high standards required for pharmaceutical R&D. A comprehensive Certificate of Analysis (COA) detailing all specifications and test results is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH Q3C guidelines
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.