Description

3-(Cbz-Amino)-Cyclobutanemethanol is a versatile and high-value pharmaceutical intermediate featuring a cyclobutane ring scaffold. This compound is crucial for medicinal chemists as it provides a rigid, four-membered carbocyclic structure for constructing novel bioactive molecules. It is primarily utilized in the research and development of new therapeutic agents, particularly within the pharmaceutical and biotechnology sectors.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates targeting various disease pathways.
• Protease Inhibitor Research: Used in the development of inhibitors for enzymes like proteases, which are relevant in virology and oncology.
• Peptidomimetic Chemistry: Serves as a constrained scaffold to mimic peptide structures, enhancing metabolic stability and bioavailability.
• Chemical Biology Probes: Employed in the creation of tool compounds for studying biological processes and target validation.
• Library Synthesis for Drug Discovery: A valuable reactant for generating diverse compound libraries in high-throughput screening campaigns.
• Agrochemical Research: Potential intermediate in the development of new active ingredients with novel modes of action.

Basic Information

Product Name	3-(Cbz-Amino)-Cyclobutanemethanol
CAS No.	130368-99-9
Molecular Formula	C13H17NO3
Molecular Weight	235.28 g/mol
Synonyms	3-[(Benzyloxycarbonyl)amino]cyclobutanemethanol; 3-[(Cbz)amino]cyclobutanemethanol; 3-(N-Cbz-amino)cyclobutanemethanol; 1-(Hydroxymethyl)-3-[(phenylmethoxy)carbonylamino]cyclobutane; Cyclobutanemethanol, 3-[(phenylmethoxy)carbonyl]amino]-; 3-Amino-1-hydroxymethylcyclobutane carbobenzoxy derivative
EINECS	Contact for details

Quality Control

We maintain a strict quality management system to ensure the consistency and purity of our pharmaceutical intermediates. Each batch of 3-(Cbz-Amino)-Cyclobutanemethanol is analyzed using advanced techniques like HPLC, NMR, and MS to verify identity and purity against established specifications. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). This material is moisture-sensitive (hygroscopic) and should be handled under an inert atmosphere for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.