Description

Methyl2-Amino-2-[3-(Trifluoromethyl)Phenyl]Acetate is a high-value, non-natural amino acid ester derivative, serving as a critical chiral building block in advanced organic synthesis. Its core value lies in the trifluoromethylphenyl group, which imparts unique electronic and steric properties essential for modulating the bioactivity and metabolic stability of target molecules. This compound is primarily needed by pharmaceutical R&D and fine chemical manufacturers for the development of novel active pharmaceutical ingredients (APIs), agrochemicals, and specialty materials.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of protease inhibitors, kinase inhibitors, and other small molecule therapeutics.
• Agrochemical Research: Used in developing advanced herbicides, fungicides, and insecticides where the trifluoromethyl group enhances lipophilicity and biological activity.
• Peptidomimetics & Bio-conjugates: Serves as a non-proteinogenic amino acid derivative for constructing modified peptides and peptide-drug conjugates.
• Ligand & Catalyst Development: Employed in the preparation of chiral ligands for asymmetric catalysis and organometallic complexes.
• Material Science Precursor: Acts as a monomer or functionalizing agent for specialty polymers and advanced organic materials.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying enzyme mechanisms and protein interactions.

Basic Information

Product Name	Methyl2-Amino-2-[3-(Trifluoromethyl)Phenyl]Acetate
CAS No.	130360-90-6
Molecular Formula	C10H10F3NO2
Molecular Weight	233.19 g/mol
Synonyms	Methyl α-Amino-3-(trifluoromethyl)benzeneacetate; Methyl 2-Amino-2-(3-trifluoromethylphenyl)acetate; (3-Trifluoromethylphenyl)glycine methyl ester; DL-3-(Trifluoromethyl)phenylglycine methyl ester; α-Amino-(3-trifluoromethyl)benzenacetic acid methyl ester; Methyl (3-trifluoromethylphenyl)glycinate; 2-Amino-2-(3-(trifluoromethyl)phenyl)acetic acid methyl ester
EINECS	Contact for details

Quality Control

Our Methyl2-Amino-2-[3-(Trifluoromethyl)Phenyl]Acetate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity assessment, to ensure it meets the high standards required for pharmaceutical and fine chemical applications. Certificates of Analysis (COA) detailing purity, enantiomeric excess, and impurity profiles are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). The product is moisture-sensitive; keep the container tightly sealed under an inert atmosphere if specified. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% e.e. (Specify enantiomer)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.