Description

3-(4-Chlorophenyl)Tropane-2-Carboxylic Acid Methyl Ester is a high-purity synthetic intermediate of significant interest in advanced organic synthesis and pharmaceutical research. Its core value lies in its role as a key precursor for the development of novel pharmacologically active compounds, particularly within the central nervous system (CNS) research domain. This compound is essential for research chemists and development teams in the pharmaceutical, biotechnology, and fine chemical industries who require reliable, high-quality building blocks for complex molecular construction.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of novel tropane alkaloid derivatives and other bioactive molecules targeting neurological pathways.
• Medicinal Chemistry Research: Serves as a versatile scaffold for structure-activity relationship (SAR) studies and the development of potential therapeutic agents.
• Reference Standard: Used as an analytical standard in method development and quality control for related pharmaceutical products and research materials.
• Organic Synthesis Building Block: Employed in complex multi-step syntheses requiring a functionalized tropane core for further chemical modification.
• Biochemical Research: Utilized in studies investigating ligand-receptor interactions and the biochemical mechanisms of related compounds.

Basic Information

Product Name	3-(4-Chlorophenyl)Tropane-2-Carboxylic Acid Methyl Ester
CAS No.	130342-80-2
Molecular Formula	C17H20ClNO2
Molecular Weight	305.80 g/mol
Synonyms	Methyl 3-(4-Chlorophenyl)-8-azabicyclo[3.2.1]octane-2-carboxylate; 3-(p-Chlorophenyl)tropane-2-carboxylic acid methyl ester; 2-Carbomethoxy-3-(4-chlorophenyl)tropane; RTI-4229-76; Contact for additional synonyms.
EINECS	Contact for details

Quality Control

Our 3-(4-Chlorophenyl)Tropane-2-Carboxylic Acid Methyl Ester is manufactured under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all relevant specifications. Our commitment is to supply material that meets the stringent requirements of research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which may affect stability and performance. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.