Description

1-[4-(Difluoromethoxy)Phenyl]Propan-1-Amine CAS NO 130339-51-4 is a specialized organic amine compound featuring a difluoromethoxy phenyl group, serving as a critical building block in advanced chemical synthesis. Its value lies in its unique molecular structure, which provides a versatile scaffold for introducing fluorinated motifs into target molecules, a key strategy in modern pharmaceutical and agrochemical design. This intermediate is essential for research and development chemists and process engineers in the pharmaceutical, agrochemical, and material science industries seeking to develop novel active ingredients with enhanced properties.

Application

• Pharmaceutical Intermediate: A key synthon for the research and production of novel active pharmaceutical ingredients (APIs), particularly in the development of central nervous system (CNS) agents and other therapeutic compounds where fluorination improves metabolic stability and bioavailability.
• Agrochemical Synthesis: Used in the manufacture of advanced herbicides, fungicides, and insecticides, where the difluoromethoxy group can enhance biological activity and environmental persistence profiles.
• Liquid Crystal & OLED Material Precursor: Serves as a starting material for synthesizing fluorinated aromatic compounds used in electronic displays and organic light-emitting diodes (OLEDs) due to its ability to modify electronic properties.
• Organic Synthesis Building Block: Employed in academic and industrial R&D for constructing complex molecules via reactions such as reductive amination, amide coupling, and nucleophilic substitution.
• Fluorine Chemistry Research: A valuable compound for studying the effects of fluorine substitution on chemical reactivity and physical properties in medicinal and materials chemistry.

Basic Information

Item	Detail
Product Name	1-[4-(Difluoromethoxy)Phenyl]Propan-1-Amine
CAS No.	130339-51-4
Molecular Formula	C10H13F2NO
Molecular Weight	201.21 g/mol
Synonyms	1-(4-(Difluoromethoxy)phenyl)propan-1-amine; 4-(Difluoromethoxy)benzenepropanamine; 1-Amino-1-(4-(difluoromethoxy)phenyl)propane; α-Methyl-4-(difluoromethoxy)benzeneethanamine; 4-(Difluoromethoxy)-β-methylphenethylamine; 1-(4-(Difluoromethoxyphenyl))propylamine; DFMPA (abbreviation)
EINECS	Contact for details

Quality Control

Our 1-[4-(Difluoromethoxy)Phenyl]Propan-1-Amine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets precise customer specifications and high-purity standards suitable for sensitive synthesis applications. Comprehensive Certificates of Analysis (COA) documenting all critical parameters are available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (typically 15-25°C). Keep away from strong oxidizing agents, strong acids, and strong bases. For long-term storage, consider an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0% (Standard Grade)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.