Description

2-Propanone, 1-(2-Pyrrolidinyl)-, (R)- (9Ci) is a chiral pyrrolidinyl ketone derivative, a high-purity intermediate of significant value in asymmetric synthesis. Its defined stereochemistry makes it a critical building block for the development of novel active pharmaceutical ingredients (APIs) and fine chemicals. This compound is essential for research and manufacturing in the pharmaceutical, agrochemical, and specialty chemical industries, where precise molecular architecture is required.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the synthesis of complex drug molecules, particularly for central nervous system (CNS) agents and other therapeutic compounds.
• Asymmetric Catalyst Ligand Precursor: Used in the development and preparation of chiral ligands for metal-catalyzed asymmetric reactions.
• Agrochemical Synthesis: Serves as a building block for creating enantiomerically pure pesticides and herbicides with improved efficacy and environmental profiles.
• Academic & Industrial R&D: A valuable reagent for methodological development in organic chemistry and medicinal chemistry research programs.
• Fine Chemical Production: Employed in the manufacture of specialty chemicals, flavors, and fragrances requiring specific stereochemical configurations.

Basic Information

Product Name	2-Propanone, 1-(2-Pyrrolidinyl)-, (R)- (9Ci)
CAS No.	130325-43-8
Molecular Formula	C7H13NO
Molecular Weight	127.18 g/mol
Synonyms	(R)-1-(2-Pyrrolidinyl)-2-propanone; (R)-1-(Pyrrolidin-2-yl)propan-2-one; (R)-2-(1-Methyl-2-oxoethyl)pyrrolidine; (R)-N-Methylpyrrolidin-2-yl methyl ketone; (R)-2-Acetonylpyrrolidine; (R)-Pyrrolidin-2-ylacetone; (R)-2-Propanone, 1-(2-pyrrolidinyl)-; (R)-Methyl 2-pyrrolidinyl ketone
EINECS	Contact for details

Quality Control

Our 2-Propanone, 1-(2-Pyrrolidinyl)-, (R)- (9Ci) is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity analysis by HPLC, to ensure it meets the high standards required for advanced synthetic applications. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.