Description

4-(Boc-Amino)Cyclohexanecarboxylic Acid is a protected amino acid derivative of significant importance in synthetic organic and medicinal chemistry. This compound serves as a crucial chiral building block for the construction of complex molecules, particularly peptides and peptidomimetics. It is primarily utilized by pharmaceutical R&D departments and fine chemical manufacturers engaged in the development of active pharmaceutical ingredients (APIs) and novel therapeutic agents.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the synthesis of peptide-based drugs and complex bioactive molecules.
• Peptide Synthesis: Used in solid-phase and solution-phase peptide synthesis to introduce a protected cyclohexylalanine analogue.
• Protease Inhibitor Development: Serves as a core structural component in the design and synthesis of protease inhibitors.
• Chemical Biology Research: Employed in the preparation of chemical probes and labeled compounds for studying biological pathways.
• Conformational Studies: Used to introduce constrained amino acid analogs into peptides to study structure-activity relationships (SAR).
• Custom Synthesis: A starting material for contract research organizations (CROs) and CDMOs for custom synthesis projects.

Basic Information

Product Name	4-(Boc-Amino)Cyclohexanecarboxylic Acid
CAS No.	130309-46-5
Molecular Formula	C₁₂H₂₁NO₄
Molecular Weight	243.30 g/mol
Synonyms	4-[(tert-Butoxycarbonyl)amino]cyclohexanecarboxylic Acid; 4-(Boc-amino)cyclohexane-1-carboxylic Acid; Boc-4-Amino-cyclohexanecarboxylic Acid; trans-4-((tert-Butoxycarbonyl)amino)cyclohexanecarboxylic Acid; 4-(tert-Butoxycarbonylamino)cyclohexanecarboxylic Acid; 4-Boc-Amino-cyclohexanecarboxylic Acid; (1r,4r)-4-[(tert-Butoxycarbonyl)amino]cyclohexane-1-carboxylic Acid; 4-N-Boc-Aminocyclohexanecarboxylic Acid
EINECS	Contact for details

Quality Control

Our 4-(Boc-Amino)Cyclohexanecarboxylic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and chiral purity assessment, to ensure it meets the high standards required for pharmaceutical R&D. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥98.0%
Chiral Purity (HPLC)	≥99.0% ee (specify isomer)
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.