Description

tert-Butyl (2-Oxotetrahydrothiophen-3-Yl)Carbamate is a high-purity, protected amino acid derivative featuring a tetrahydrothiophene scaffold. This compound is a critical pharmaceutical intermediate and building block in advanced organic synthesis, valued for its role in constructing complex molecular architectures. It is primarily utilized by research institutions and manufacturers in the pharmaceutical and agrochemical industries for the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of protease inhibitors and other small molecule therapeutics.
• Peptidomimetic Research: Used to introduce constrained, sulfur-containing amino acid analogs into peptide chains to modulate biological activity and stability.
• Agrochemical Synthesis: Serves as a precursor in the development of new herbicides and fungicides with novel modes of action.
• Chemical Biology Probes: Employed in the creation of activity-based probes for studying enzyme function and mechanism.
• Material Science: Potential monomer or additive in the synthesis of specialized polymers with unique properties.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs for the production of client-specific target molecules under cGMP conditions.

Basic Information

Product Name	tert-Butyl (2-Oxotetrahydrothiophen-3-Yl)Carbamate
CAS No.	130288-32-3
Molecular Formula	C9H15NO3S
Molecular Weight	217.29 g/mol
Synonyms	3-[[(1,1-Dimethylethoxy)carbonyl]amino]tetrahydro-2-thiophenone; 3-[(tert-Butoxycarbonyl)amino]dihydro-2(3H)-thiophenone; Boc-3-ATHP; tert-Butyl N-(2-oxotetrahydrothiophen-3-yl)carbamate; 3-(Boc-amino)tetrahydrothiophen-2-one; (2-Oxo-tetrahydro-thiophen-3-yl)-carbamic acid tert-butyl ester; 3-Amino-2-tetrahydrothiophenone, N-Boc-protected; BOC-3-Aminotetrahydrothiophen-2-one
EINECS	Contact for details

Quality Control

Our tert-Butyl (2-Oxotetrahydrothiophen-3-Yl)Carbamate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment. We support development and commercial projects with material suitable for research use through to cGMP standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere if opened, and desiccate if necessary for long-term storage.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥98.0%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm
Single Unknown Impurity (HPLC)	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.