Description

N(4)-Oleylcytosine Arabinoside is a chemically modified nucleoside analog, specifically an N4-acyl derivative of cytarabine. This compound is significant for its potential as a lipophilic prodrug, designed to enhance cellular uptake and bioavailability compared to its parent molecule. It is primarily of interest to researchers and developers in the pharmaceutical and biotechnology sectors for advanced drug delivery applications, particularly in oncology and antiviral therapy development.

Application

• Pharmaceutical Research: Serves as a key intermediate or active pharmaceutical ingredient (API) in the development of novel chemotherapeutic and antiviral agents.
• Prodrug Development: Utilized in studies focusing on lipophilic prodrug strategies to improve the pharmacokinetic profile and therapeutic efficacy of nucleoside analogs.
• Oncology R&D: Investigated for its potential activity against various cancer cell lines, leveraging the cytarabine (ara-C) mechanism with modified delivery.
• Bioconjugation Studies: Acts as a building block for conjugating nucleoside therapeutics with lipids or other carriers for targeted delivery systems.
• Biochemical Tool: Used in laboratory research to study enzyme interactions, cellular metabolism, and resistance mechanisms related to nucleoside-based drugs.

Basic Information

Product Name	N(4)-Oleylcytosine Arabinoside
CAS No.	130252-71-0
Molecular Formula	C₃₂H₅₅N₃O₅
Molecular Weight	561.80 g/mol
Synonyms	1-β-D-Arabinofuranosyl-4-oleoylaminopyrimidin-2(1H)-one; N4-Oleoyl-1-β-D-arabinofuranosylcytosine; Cytarabine N4-oleate; Oleylcytosine Arabinoside; N4-Oleoylcytosine Arabinoside; N4-Oleoyl-ara-C; 4-Oleoylamino-1-β-D-arabinofuranosyl-2(1H)-pyrimidinone
EINECS	Contact for details

Quality Control

Our N(4)-Oleylcytosine Arabinoside is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and MS for structural confirmation, and tests for residual solvents and moisture. We provide a detailed Certificate of Analysis (COA) with every shipment to ensure traceability and compliance with your research or development specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C or as indicated on the label or COA. This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 2.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.