Description

(R,S)-Methyl-2-(2-Chlorophenyl)-2-(4,5,6,7-Tetrahydrothieno[3,2-c]pyridin-5-yl)acetate hydrochloride is a high-purity chemical intermediate of significant importance in modern pharmaceutical synthesis. Its value lies in its role as a key building block for the development of active pharmaceutical ingredients (APIs), particularly those targeting the central nervous system. This compound is essential for research institutions and manufacturers engaged in the development and production of advanced therapeutic agents.

Application

This versatile chemical intermediate serves critical functions in several high-value industrial and research sectors:

• Pharmaceutical Intermediate: Primary use as a key building block in the synthesis of novel Active Pharmaceutical Ingredients (APIs).
• Neurological Drug Research: Integral in the R&D of compounds targeting neurological receptors and pathways.
• Process Chemistry: Used in scale-up and optimization studies for commercial drug manufacturing processes.
• Reference Standard: Serves as a high-purity analytical standard for quality control and method development in pharmaceutical analysis.
• Academic & Institutional Research: Employed in medicinal chemistry programs for structure-activity relationship (SAR) studies.
• Custom Synthesis: A starting material for the contract synthesis of more complex, proprietary molecules.

Basic Information

Product Name	(R,S)-Methyl-2-(2-Chlorophenyl)-2-(4,5,6,7-Tetrahydrothieno[3,2-c]pyridin-5-yl)acetate hydrochloride
CAS No.	130209-90-4
Molecular Formula	C₁₇H₁₈ClNO₂S•HCl
Molecular Weight	364.31 g/mol
Synonyms	Methyl 2-(2-chlorophenyl)-2-(4,5,6,7-tetrahydrothieno[3,2-c]pyridin-5-yl)acetate hydrochloride; (±)-Methyl 2-(2-chlorophenyl)-2-(6,7-dihydro-4H-thieno[3,2-c]pyridin-5(4H)-yl)acetate hydrochloride; Clopidogrel Intermediate; SR 25989 intermediate; 130209-90-4; 5-[Methoxycarbonyl(2-chlorophenyl)methyl]-4,5,6,7-tetrahydrothieno[3,2-c]pyridine hydrochloride
EINECS	Contact for details

Quality Control

Our production of (R,S)-Methyl-2-(2-Chlorophenyl)-2-(4,5,6,7-Tetrahydrothieno[3,2-c]pyridin-5-yl)acetate hydrochloride adheres to stringent quality management protocols. Every batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the exacting standards required for pharmaceutical intermediate applications. Certificates of Analysis (COA) detailing all specifications and test results are provided and available upon request to support your regulatory and quality assurance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.5%
Related Substances (HPLC)	Total impurities ≤ 1.5% Any single impurity ≤ 0.5%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.