Description

(S)-Methyl 4-(Boc-(Methyl)Amino)-5-Hydroxypentanoate is a high-purity chiral building block and protected amino acid derivative essential for advanced organic synthesis. Its value lies in providing a stereochemically defined scaffold with orthogonal protecting groups, enabling the efficient and controlled construction of complex molecules. This compound is critically needed by research institutions and pharmaceutical companies engaged in the development of peptide mimetics, active pharmaceutical ingredients (APIs), and other bioactive compounds.

Application

• Pharmaceutical Intermediate: Key chiral synthon in the synthesis of novel drug candidates and active pharmaceutical ingredients (APIs).
• Peptidomimetic Research: Serves as a crucial building block for designing and synthesizing peptide analogs and mimetics with enhanced stability and bioavailability.
• Asymmetric Synthesis: Used in stereoselective reactions to introduce chiral centers in complex organic molecules.
• Protecting Group Chemistry: The tert-butoxycarbonyl (Boc) and methyl ester groups allow for sequential deprotection and selective functionalization.
• Bioconjugation & Probe Development: Useful for creating labeled compounds and molecular probes for biochemical and diagnostic applications.
• Academic & Process Chemistry: Employed in method development, scale-up studies, and the discovery of new synthetic routes in both academic and industrial R&D settings.

Basic Information

Product Name	(S)-Methyl 4-(Boc-(Methyl)Amino)-5-Hydroxypentanoate
CAS No.	130205-54-8
Molecular Formula	C₁₂H₂₃NO₅
Molecular Weight	261.31 g/mol
Synonyms	Methyl (4S)-4-[[(1,1-Dimethylethoxy)carbonyl](methyl)amino]-5-hydroxypentanoate; (S)-Methyl 4-[(tert-Butoxycarbonyl)(methyl)amino]-5-hydroxypentanoate; (S)-4-(N-Boc-N-Methylamino)-5-Hydroxypentanoic Acid Methyl Ester; Boc-N(Me)-Ahp(5-OH)-OMe; (S)-Methyl 5-hydroxy-4-[(2-methylpropan-2-yl)oxycarbonyl(methyl)amino]pentanoate; (4S)-4-[(tert-Butoxycarbonyl)(methyl)amino]-5-hydroxypentanoic Acid Methyl Ester
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. Each batch is characterized to confirm identity, purity, and chiral integrity. Certificates of Analysis (COA) detailing specific results for assay, enantiomeric excess, and impurity profiles are available upon request. We adhere to cGMP principles for the manufacture of materials intended for pharmaceutical research and development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥97.0%
Enantiomeric Excess (Chiral HPLC)	≥98.0%
Water Content (KF)	≤1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.