Description

1-[2-Amino-1-(4-Methoxyphenyl)-Ethyl]-Cyclohexanol Hydrochloride is a high-purity pharmaceutical intermediate and chiral building block of significant importance in modern organic synthesis. Its value lies in its structural complexity, which serves as a key precursor in the development of active pharmaceutical ingredients (APIs) and fine chemicals. This compound is primarily needed by research institutions, pharmaceutical manufacturers, and fine chemical producers engaged in the synthesis of novel therapeutic agents and complex organic molecules.

Application

• Pharmaceutical Intermediate: A critical chiral synthon in the multi-step synthesis of complex drug candidates, particularly in central nervous system (CNS) and cardiovascular research.
• API Development: Serves as a key building block for the research and production of novel Active Pharmaceutical Ingredients (APIs).
• Asymmetric Synthesis: Utilized in stereoselective reactions to construct molecules with specific three-dimensional configurations essential for biological activity.
• Fine Chemical Production: Employed in the manufacture of high-value specialty chemicals for advanced material science and agrochemical research.
• Academic & Industrial R&D: Used in laboratory-scale research for method development and exploring new synthetic pathways in medicinal chemistry.
• Reference Standard: Can be supplied as a high-purity analytical standard for quality control and method validation in pharmaceutical analysis.

Basic Information

Product Name	1-[2-Amino-1-(4-Methoxyphenyl)-Ethyl]-Cyclohexanol Hydrochloride
CAS No.	130198-05-9
Molecular Formula	C15H24ClNO2
Molecular Weight	285.81 g/mol
Synonyms	1-[2-Amino-1-(4-Methoxyphenyl)ethyl]cyclohexanol hydrochloride; (1R,2S)-1-(4-Methoxyphenyl)-2-(1-hydroxycyclohexyl)-2-aminoethane hydrochloride; (1R,2S)-1-(p-Methoxyphenyl)-2-(1-hydroxycyclohexyl)-2-aminoethane HCl; 1-(2-Amino-1-(4-methoxyphenyl)ethyl)cyclohexanol HCl; Cyclohexanol, 1-[2-amino-1-(4-methoxyphenyl)ethyl]-, hydrochloride; (1R,2S)-Rel-1-(4-Methoxyphenyl)-2-(1-hydroxycyclohexyl)-2-aminoethane hydrochloride
EINECS	Contact for details

Quality Control

Our 1-[2-Amino-1-(4-Methoxyphenyl)-Ethyl]-Cyclohexanol Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity assessment, to ensure it meets the high standards required for pharmaceutical R&D and production. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are available upon request. We can supply material compliant with current Good Manufacturing Practice (cGMP) principles for advanced applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Chiral Purity (Chiral HPLC)	≥99.0% ee
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm
Related Substances (HPLC)	Total impurities ≤2.0%; Any single impurity ≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.