Description

n-Succinimidyl-2,4-Dimethoxy-3-(Trimethylstannyl)Benzoate is a specialized organotin reagent used as a key intermediate in advanced organic synthesis. Its core value lies in enabling the efficient introduction of the 2,4-dimethoxy-3-(trimethylstannyl)benzoyl moiety into target molecules via stable amide bond formation. This compound is essential for researchers and manufacturers in pharmaceutical development, particularly in the synthesis of complex active pharmaceutical ingredients (APIs) and for creating bioconjugates in radiopharmaceutical and diagnostic agent research.

Application

• Pharmaceutical Intermediate: Critical building block for the synthesis of novel drug candidates and active pharmaceutical ingredients (APIs).
• Radiopharmaceutical Precursor: Used in the development of diagnostic imaging agents, where the tin moiety can serve as a precursor for radioiodination or other radiolabeling techniques.
• Bioconjugation Chemistry: Facilitates the site-specific labeling of peptides, proteins, and antibodies with reporter molecules or therapeutic payloads.
• Material Science Research: Employed in the synthesis of functionalized polymers and advanced organic materials with tailored properties.
• Cross-Coupling Reactions: Acts as a stamane reagent in Stille cross-coupling reactions to form carbon-carbon bonds in complex molecule assembly.
• Chemical Biology Probes: Integral for creating molecular probes used to study biological pathways and protein function.

Basic Information

Product Name	n-Succinimidyl-2,4-Dimethoxy-3-(Trimethylstannyl)Benzoate
CAS No.	130168-12-6
Molecular Formula	C₁₈H₂₅NO₆Sn
Molecular Weight	470.10 g/mol
Synonyms	2,5-Dioxopyrrolidin-1-yl 2,4-dimethoxy-3-(trimethylstannyl)benzoate; 3-(Trimethylstannyl)-2,4-dimethoxybenzoic Acid N-Hydroxysuccinimide Ester; NHS Ester of 3-(Trimethylstannyl)-2,4-dimethoxybenzoic Acid; 2,4-Dimethoxy-3-(trimethylstannyl)benzoic Acid Succinimidyl Ester; 3-(Trimethylstannyl)-2,4-dimethoxybenzoyloxysuccinimide; SnMe3-DMB-NHS Ester; TMT-DMB-OSu
EINECS	Contact for details

Quality Control

Our n-Succinimidyl-2,4-Dimethoxy-3-(Trimethylstannyl)Benzoate is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity for research and development applications. We provide comprehensive Certificates of Analysis (COA) with each batch, detailing key parameters such as purity, identity, and impurity profiles. Our quality system is designed to support cGMP-compliant workflows for advanced pharmaceutical synthesis.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C (refrigerated) or as indicated on the label or COA. This product is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) when possible to maintain stability. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥95%
Water Content (KF)	≤1.0%
Tin (Sn) Content	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.