Description

1,3-Benzenediol, 5-[1-Hydroxy-2-[[2-(4-Hydroxyphenyl)-1-Methylethyl]Amino]Ethyl]-, (R*,R*)-(+-)- is a complex synthetic organic compound of significant interest in advanced pharmaceutical research and development. This molecule is valued for its specific stereochemistry and functional groups, which make it a crucial intermediate in the synthesis of targeted active pharmaceutical ingredients (APIs). It is primarily sought by R&D chemists and process development scientists in the pharmaceutical and fine chemical industries. The compound, identified by CAS number 130156-24-0, requires expert handling and high-purity supply to ensure successful downstream application.

Application

• Pharmaceutical Intermediate: Serves as a key chiral building block in the synthesis of novel adrenergic receptor agonists or other specialized therapeutic agents.
• Biochemical Research: Used as a reference standard or precursor in studies investigating receptor-ligand interactions and signal transduction pathways.
• Process Chemistry: Employed in route scouting and optimization for the commercial-scale production of complex drug molecules.
• Asymmetric Synthesis: Utilized in catalytic reactions to construct molecules with defined stereocenters due to its inherent chiral structure.
• Analytical Standard: Provides a high-purity benchmark for method development and quality control in analytical laboratories (HPLC, LC-MS).

Basic Information

Product Name	1,3-Benzenediol, 5-[1-Hydroxy-2-[[2-(4-Hydroxyphenyl)-1-Methylethyl]Amino]Ethyl]-, (R*,R*)-(+-)-
CAS No.	130156-24-0
Molecular Formula	C17H21NO4
Molecular Weight	303.35 g/mol
Synonyms	(±)-erythro-1-(3,5-Dihydroxyphenyl)-2-[(1-methyl-2-(4-hydroxyphenyl)ethyl)amino]ethanol; Racemic Erythro Dihydroxyphenyl Ethanolamine Derivative; 5-[1-Hydroxy-2-({2-[4-hydroxyphenyl]-1-methylethyl}amino)ethyl]benzene-1,3-diol; Adrenergic Phenethanolamine Intermediate; 1,3-Benzenediol, 5-[1-hydroxy-2-[[2-(4-hydroxyphenyl)-1-methylethyl]amino]ethyl]-, (±)-erythro-; 130156-24-0; Benzenediol Adrenergic Agent Intermediate
EINECS	Contact for details

Quality Control

Our production of this advanced intermediate adheres to strict quality management systems, ensuring batch-to-batch consistency for critical R&D and scale-up work. Quality is verified through comprehensive analytical techniques including HPLC for purity and chiral assay, NMR, and MS for structural confirmation. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting identity, purity, and impurity profiles. We support compliance with ICH guidelines for impurities and can tailor specifications to meet specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at a controlled room temperature (15-25°C) to minimize oxidation and degradation. The container should be kept in a cool, dry, and well-ventilated area, separate from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Chiral Purity	≥ 99.0% erythro diastereomer
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.