Description

(R,S)-2-Amino-3-[3-(Carboxymethoxy)-5-Methyl-Isoxazol-4-Yl]-Propionic Acid, Sesquihydrate is a high-purity, non-proteinogenic amino acid derivative featuring a unique isoxazole ring system. This compound is valued for its role as a key synthetic intermediate and a versatile building block in advanced organic synthesis. It is primarily sought after by research institutions and pharmaceutical development companies for applications in medicinal chemistry, including the synthesis of novel bioactive molecules and potential drug candidates.

Application

• Pharmaceutical Intermediate: Serves as a critical building block in the research and development of new active pharmaceutical ingredients (APIs), particularly those targeting neurological or metabolic pathways.
• Medicinal Chemistry Research: Used as a scaffold or precursor for creating compound libraries in high-throughput screening for drug discovery programs.
• Biochemical Research: Acts as a substrate or inhibitor analog in enzymatic studies, leveraging its structural similarity to natural amino acids.
• Peptidomimetics: Incorporated into synthetic peptides to modify their stability, bioavailability, or receptor binding affinity.
• Agrochemical Research: Explored as an intermediate in the synthesis of novel herbicides or plant growth regulators due to its heterocyclic structure.
• Chemical Biology Probes: Utilized in the development of labeled compounds or probes for studying biological processes at the molecular level.

Basic Information

Product Name	(R,S)-2-Amino-3-[3-(Carboxymethoxy)-5-Methyl-Isoxazol-4-Yl]-Propionic Acid, Sesquihydrate
CAS No.	130146-18-8
Molecular Formula	C9H12N2O6 • 1.5H2O
Molecular Weight	267.22 g/mol (Anhydrous basis)
Synonyms	2-Amino-3-[3-(carboxymethoxy)-5-methyl-4-isoxazolyl]propionic acid sesquihydrate; (RS)-AMOA sesquihydrate; AMOA, (R,S)-, sesquihydrate; 4-Isoxazolepropanoic acid, α-amino-3-(carboxymethoxy)-5-methyl-, sesquihydrate, (±)-; DL-2-Amino-3-(3-carboxymethoxy-5-methylisoxazol-4-yl)propionic acid sesquihydrate; (Rac)-AMOA sesquihydrate; NSC 339222 (sesquihydrate)
EINECS	Contact for details

Quality Control

Every batch of (R,S)-2-Amino-3-[3-(Carboxymethoxy)-5-Methyl-Isoxazol-4-Yl]-Propionic Acid, Sesquihydrate is manufactured and tested under a strict quality management system. We ensure compliance with relevant industry standards for research-grade chemicals. Comprehensive analytical testing, including HPLC for purity and identity confirmation, is performed. Certificates of Analysis (COA) detailing all specification results are provided with each shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept under dry, inert conditions to maintain stability and purity. For long-term storage, consider desiccated or inert atmosphere packaging.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	8.0 - 11.0% (Theoretical for Sesquihydrate: ~10.1%)
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.