Description

2-Methyl-n-(Phenylmethylene)Alanine Ethyl Ester is a specialized chiral building block and intermediate of significant interest in advanced organic synthesis. This compound matters for its role in constructing complex molecular architectures, particularly in the development of pharmaceuticals and bioactive compounds. It is primarily needed by research chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for applications in asymmetric synthesis and medicinal chemistry.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of novel active pharmaceutical ingredients (APIs), particularly for compounds requiring specific stereochemistry.
• Asymmetric Synthesis: Used as a building block in stereoselective reactions to introduce the 2-methylalanine moiety into target molecules.
• Peptidomimetics Research: Serves as a constrained amino acid analog in the design and synthesis of peptide mimics for drug discovery programs.
• Agrochemical Development: Employed as an intermediate in the synthesis of advanced crop protection agents with specific biological activity.
• Ligand and Catalyst Preparation: Useful in the preparation of chiral ligands and organocatalysts for use in enantioselective transformations.
• Academic and R&D Laboratories: A valuable reagent for methodological studies in organic chemistry and for exploring new synthetic pathways.

Basic Information

Item	Detail
Product Name	2-Methyl-n-(Phenylmethylene)Alanine Ethyl Ester
CAS No.	130146-17-7
Molecular Formula	C₁₃H₁₇NO₂
Molecular Weight	219.28 g/mol
Synonyms	Ethyl 2-Methyl-N-(phenylmethylene)alaninate; (2S)-2-Methyl-N-(phenylmethylidene)alanine ethyl ester; N-Benzylidene-2-methylalanine ethyl ester; 2-Methylalanine N-benzylidene ethyl ester; Alanine, N-(phenylmethylene)-, ethyl ester, 2-methyl-; (S)-2-Methyl-N-benzylidenealanine ethyl ester; Ethyl (S)-2-methyl-N-(phenylmethylene)alaninate
EINECS	Contact for details

Quality Control

Our 2-Methyl-n-(Phenylmethylene)Alanine Ethyl Ester is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity assessment by HPLC, to ensure it meets the high standards required for research and development applications. Certificates of Analysis (COA) detailing identity, purity, and chiral excess are available upon request to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at controlled room temperature (15-25°C). This material is easily oxidized and should be handled and stored under an inert atmosphere such as nitrogen or argon for long-term stability. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or low-melting solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee (enantiomeric excess)
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.