Description

(R)-6-Benzyloxymethyl-4-Methyl-5,6-Dihydro-Pyran-2-One CAS NO 130129-10-1 is a chiral lactone derivative of significant synthetic utility. This compound serves as a crucial advanced pharmaceutical intermediate (API) and a versatile building block in asymmetric synthesis. It is primarily required by research and development teams in the pharmaceutical and fine chemical sectors for the production of optically active target molecules. Its defined stereochemistry and functional group array make it a valuable precursor for complex drug discovery programs.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the synthesis of active pharmaceutical ingredients (APIs) requiring specific stereochemistry.
• Asymmetric Synthesis: Used as a building block for constructing complex natural products and bioactive compounds with high enantiomeric purity.
• Medicinal Chemistry Research: Employed in drug discovery and development for creating novel molecular entities and exploring structure-activity relationships (SAR).
• Catalyst and Ligand Development: Serves as a precursor for chiral auxiliaries, catalysts, or ligands used in enantioselective transformations.
• Fine Chemical Production: Utilized in the multi-step synthesis of specialty chemicals, flavors, and fragrances where optical purity is critical.
• Academic and Industrial R&D: A valuable reagent for methodological studies in organic chemistry and process development.

Basic Information

Product Name	(R)-6-Benzyloxymethyl-4-Methyl-5,6-Dihydro-Pyran-2-One
CAS No.	130129-10-1
Molecular Formula	C14H16O3
Molecular Weight	232.28 g/mol
Synonyms	(R)-6-(Benzyloxymethyl)-4-methyl-5,6-dihydro-2H-pyran-2-one; (6R)-6-[(Phenylmethoxy)methyl]-4-methyl-3,6-dihydro-2H-pyran-2-one; (R)-4-Methyl-6-(benzyloxymethyl)-5,6-dihydro-2H-pyran-2-one; (R)-6-(Benzyloxymethyl)-4-methyl-3,6-dihydro-2H-pyran-2-one; (R)-6-(Benzyloxymethyl)-4-methyl-5,6-dihydro-2-pyranone; (R)-4-Methyl-6-(benzyloxymethyl)-5,6-dihydro-2H-pyran-2-one; (R)-6-(Benzyloxymethyl)-4-methyl-3,6-dihydro-2H-pyran-2-one; (R)-6-(Benzyloxymethyl)-4-methyl-5,6-dihydro-2H-pyran-2-one
EINECS	Contact for details

Quality Control

Our (R)-6-Benzyloxymethyl-4-Methyl-5,6-Dihydro-Pyran-2-One is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral HPLC for enantiomeric excess (ee) and standard purity assays, to ensure it meets the high standards required for pharmaceutical R&D. Certificates of Analysis (COA) with detailed specifications are available upon request to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). This material may be sensitive to moisture and prolonged exposure to air; it is recommended to handle and store under an inert atmosphere for long-term stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.