Description

n-(3-Isopropylamino-2-Hydroxypropyl) Pindolol is a key pharmaceutical intermediate and a derivative of the β-blocker pindolol. This compound is valued for its role in the synthesis and research of advanced cardiovascular and neurological active pharmaceutical ingredients (APIs). It is primarily required by pharmaceutical R&D laboratories, fine chemical manufacturers, and academic research institutions engaged in drug discovery and process development.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of pindolol and related β-adrenergic blocking agents.
• Research & Development: Used in medicinal chemistry for the design and development of new cardiovascular and neurological drug candidates.
• Reference Standard: Serves as a high-purity analytical standard for quality control and method validation in pharmaceutical analysis.
• Process Chemistry: Employed in route scouting and optimization for the commercial-scale manufacturing of β-blocker APIs.
• Biochemical Research: Utilized in studies investigating β-adrenergic receptor mechanisms and related pharmacological pathways.

Basic Information

Product Name	n-(3-Isopropylamino-2-Hydroxypropyl) Pindolol
CAS No.	130115-63-8
Molecular Formula	C20H33N3O3
Molecular Weight	363.50 g/mol
Synonyms	1-(1H-Indol-4-yloxy)-3-[(1-methylethyl)amino]-2-propanol; 4-[2-Hydroxy-3-[(1-methylethyl)amino]propoxy]-1H-indole; Pindolol Impurity; Pindolol Related Compound A; Pindolol EP Impurity A; Isopropylamino Hydroxypropyl Pindolol; 130115-63-8; Pindolol Derivative
EINECS	Contact for details

Quality Control

Our n-(3-Isopropylamino-2-Hydroxypropyl) Pindolol is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide full traceability and Certificates of Analysis (COA) are available for all shipments, supporting compliance with cGMP and ICH guidelines for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere or in a desiccator after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 1.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.