Description

Methyl 3-(4-Fluorophenylamino)-3-Oxopropanoate is a high-purity fluorinated organic intermediate of significant importance in advanced chemical synthesis. This compound is valued for its role as a key building block in the development of active pharmaceutical ingredients (APIs) and other fine chemicals. It is primarily needed by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries seeking to incorporate a fluorinated anilide moiety into complex molecular architectures.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and metabolic diseases.
• Agrochemical Synthesis: Used in the research and development of advanced herbicides and fungicides, where the fluorine atom enhances biological activity and stability.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the development of organic semiconductors, liquid crystals, and polymers with specific electronic or optical properties.
• Custom Synthesis and Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of client-specific target molecules.

Basic Information

Product Name	Methyl 3-(4-Fluorophenylamino)-3-Oxopropanoate
CAS No.	130112-64-0
Molecular Formula	C10H10FNO3
Molecular Weight	211.19 g/mol
Synonyms	Methyl 3-((4-fluorophenyl)amino)-3-oxopropanoate; 3-((4-Fluorophenyl)amino)-3-oxopropanoic acid methyl ester; Methyl 4-fluoroacetoacetate anilide; Methyl β-(4-fluoroanilino)-β-oxopropionate; Acetoacetic acid 4-fluoroanilide methyl ester; Methyl 3-oxo-3-(4-fluoroanilino)propanoate; N-(4-Fluorophenyl)-3-methoxy-3-oxopropanamide
EINECS	Contact for details

Quality Control

Our Methyl 3-(4-Fluorophenylamino)-3-Oxopropanoate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and identity confirmation. Certificates of Analysis (COA) detailing all specifications are provided with every shipment. We can supply material compliant with cGMP standards for pharmaceutical development upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong oxidizing agents, strong acids, and strong bases. The container should be kept tightly sealed in a dry environment to minimize moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.