Description

3-Hydroxy-10,11-Dihydroquinidine is a high-purity, advanced pharmaceutical intermediate derived from the cinchona alkaloid family. This compound is valued for its specific stereochemistry and functional groups, making it a critical building block in the synthesis of complex chiral molecules. It is primarily sought after by research institutions and manufacturers in the pharmaceutical and fine chemical sectors for developing new therapeutic agents and conducting advanced chemical studies.

Application

• Pharmaceutical Intermediate: A key chiral precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for cardiovascular and anti-malarial drug candidates.
• Asymmetric Catalysis: Used as a ligand or catalyst precursor in stereoselective organic synthesis to create enantiomerically pure compounds.
• Chemical Research & Development: Serves as a standard or reference material in analytical method development and pharmacological studies.
• Fine Chemical Synthesis: Employed in the multi-step synthesis of complex natural product analogs and specialty chemicals.

Basic Information

Product Name	3-Hydroxy-10,11-Dihydroquinidine
CAS No.	130061-81-3
Molecular Formula	C20H26N2O2
Molecular Weight	326.43 g/mol
Synonyms	10,11-Dihydro-3-hydroxyquinidine; (8S,9R)-10,11-Dihydro-6'-methoxycinchonan-9-ol; 3-Hydroxydihydroquinidine; Quinidine, 10,11-dihydro-3-hydroxy-; 3-Hydroxy-10,11-dihydroquinidine base
EINECS	Contact for details

Quality Control

Our 3-Hydroxy-10,11-Dihydroquinidine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and chiral purity assessment, to ensure it meets exacting standards for research and production use. A Certificate of Analysis (COA) detailing identity, purity, and specific test results is provided with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep the container tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity	≥ 99.0% ee
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.