Description

3-[2-[4-(6-Fluoro-1,2-Benzisoxazol-3-Yl)-1-Piperidinyl]Ethyl]-6,7,8,9-Tetrahydro-7-Methoxy-2-Methyl-4H-Pyrido[1,2-A]Pyrimidin-4-One is a high-purity pharmaceutical intermediate and research chemical with a complex heterocyclic structure. This compound is of significant value for its role in the synthesis and development of advanced active pharmaceutical ingredients (APIs). It is primarily sought by research institutions and pharmaceutical manufacturers engaged in the development of novel therapeutic agents.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of complex drug molecules, particularly in central nervous system (CNS) research.
• Active Pharmaceutical Ingredient (API) Development: Serves as a core structural component for the research and development of new therapeutic compounds.
• Biochemical Research: Used in pharmacological studies to investigate receptor binding and biological activity.
• Process Chemistry & Scale-Up: Employed in route scouting and optimization for the commercial-scale production of target molecules.
• Reference Standard: Utilized as an analytical standard for quality control and method validation in pharmaceutical laboratories.
• Contract Research & Manufacturing (CRAM): Supplied to organizations specializing in custom synthesis and development services.

Basic Information

Product Name	3-[2-[4-(6-Fluoro-1,2-Benzisoxazol-3-Yl)-1-Piperidinyl]Ethyl]-6,7,8,9-Tetrahydro-7-Methoxy-2-Methyl-4H-Pyrido[1,2-A]Pyrimidin-4-One
CAS No.	130049-83-1
Molecular Formula	C25H29FN4O3
Molecular Weight	452.53 g/mol
Synonyms	6-Fluoro-3-(4-(2-(7-methoxy-2-methyl-4-oxo-3,4,6,7,8,9-hexahydro-2H-pyrido[1,2-a]pyrimidin-3-yl)ethyl)piperidin-1-yl)benzo[d]isoxazole; Iloperidone Intermediate; HP 873 Intermediate; Fanapta Intermediate; 1-(4-(6-Fluoro-1,2-benzisoxazol-3-yl)piperidin-1-yl)-2-(7-methoxy-2-methyl-4-oxo-3,4,6,7,8,9-hexahydro-2H-pyrido[1,2-a]pyrimidin-3-yl)ethane; Iloperidone Key Intermediate; CAS 130049-83-1
EINECS	Contact for details

Quality Control

Our 3-[2-[4-(6-Fluoro-1,2-Benzisoxazol-3-Yl)-1-Piperidinyl]Ethyl]-6,7,8,9-Tetrahydro-7-Methoxy-2-Methyl-4H-Pyrido[1,2-A]Pyrimidin-4-One is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment. We can supply material compliant with current ICH guidelines for impurities and stability.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). The container should be kept tightly sealed in a dry environment to protect the product from moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 1.0%
Residual Solvents (GC)	Complies with ICH Q3C
Loss on Drying	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.