Description

Carbomethoxycarbonyl-D-Pro-D-Phe Benzyl Ester is a high-purity, synthetic dipeptide derivative used as a critical building block in advanced pharmaceutical research and development. This compound is essential for the synthesis of complex peptide-based molecules, offering researchers precise control over stereochemistry and molecular architecture. It is primarily utilized by pharmaceutical R&D laboratories, biotechnology companies, and academic institutions focused on developing novel therapeutic agents, particularly in the fields of oncology, metabolic disorders, and neurology.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the multi-step synthesis of complex peptide drugs and peptidomimetics.
• Protease Inhibitor Research: Used in the development and study of inhibitors targeting specific proteolytic enzymes.
• Solid-Phase Peptide Synthesis (SPPS): Serves as a protected dipeptide unit for the efficient construction of longer peptide chains.
• Medicinal Chemistry: Employed in structure-activity relationship (SAR) studies to optimize the potency and selectivity of lead compounds.
• Bioconjugation: Can be utilized in the preparation of peptide-drug conjugates (PDCs) and other targeted therapeutic platforms.
• Reference Standard: Acts as a high-purity analytical standard for quality control and method development in analytical laboratories.

Basic Information

Product Name	Carbomethoxycarbonyl-D-Pro-D-Phe Benzyl Ester
CAS No.	129988-00-7
Molecular Formula	C24H26N2O6
Molecular Weight	438.48 g/mol
Synonyms	Benzyl N-[(benzyloxy)carbonyl]-D-phenylalanyl-D-prolinate; Z-D-Phe-D-Pro-OBzl; (Benzyloxy)carbonyl-D-phenylalanyl-D-proline benzyl ester; Cbz-D-Phe-D-Pro-OBzl; N-Carbobenzoxy-D-phenylalanyl-D-proline benzyl ester; D-Phenylalanyl-D-proline, N-[(phenylmethoxy)carbonyl]-, phenylmethyl ester; Z-D-Phenylalanyl-D-proline benzyl ester
EINECS	Contact for details

Quality Control

Our Carbomethoxycarbonyl-D-Pro-D-Phe Benzyl Ester is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis, and identity confirmation via spectroscopic methods, to ensure it meets the exacting standards required for pharmaceutical research. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting batch-specific results for critical parameters such as assay, chiral purity, and related substances.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); ensure the container is sealed tightly after each use to prevent degradation from atmospheric moisture. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% de
Related Substances (HPLC)	Total impurities ≤ 2.0%
Any single unknown impurity	≤ 0.5%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.