Description

Ethyl 21,21,21-Trifluoroapovincaminate is a high-purity synthetic derivative of the Vinca alkaloid family, specifically designed for advanced pharmaceutical research and development. This compound is valued for its potential as a key intermediate in the synthesis of novel therapeutic agents targeting neurological and cardiovascular systems. It is primarily utilized by research institutions, pharmaceutical manufacturers, and fine chemical suppliers engaged in the development of next-generation drugs.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of novel active pharmaceutical ingredients (APIs) for neurological research.
• Biochemical Research: Used as a reference standard or reagent in studies investigating cellular mechanisms and receptor binding.
• Preclinical Development: Serves as a key material in the early-stage development and optimization of new drug candidates.
• Fine Chemical Synthesis: Employed in custom synthesis and process development for specialized, high-value chemical entities.
• Academic Research: Utilized in university and institutional labs for pharmacological and chemical exploration.

Basic Information

Product Name	Ethyl 21,21,21-Trifluoroapovincaminate
CAS No.	129959-03-1
Molecular Formula	C24H27F3N2O3
Molecular Weight	448.48 g/mol
Synonyms	Ethyl 21,21,21-Trifluoroapovincaminate; 21,21,21-Trifluoroapovincaminic Acid Ethyl Ester; Apovincaminic Acid, 21,21,21-Trifluoro-, Ethyl Ester; Ethyl (3α,16α)-Eburnamenine-14-carboxylate 21,21,21-Trifluoro Derivative; VIN-21,21,21-F3 Ethyl Ester; Contact for additional synonyms.
EINECS	Contact for details

Quality Control

Our Ethyl 21,21,21-Trifluoroapovincaminate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation (IR, NMR), to ensure it meets exacting standards for research and development use. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Residual Solvents (GC)	Complies with ICH guidelines
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.